Effect of the sol-gel condition on photostability and optical properties of alkoxy-substituted zinc phthalocyanine in the hybrid glass matrix

Popanda, Barbara; Grolik, Jarosław; Gieszczyk, W.; Środa, Marcin

doi:10.1016/j.dyepig.2023.111142

Cited by 3 publications

(1 citation statement)

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“…Absorption and fluorescence spectra of the samples were measured on a Shimadzu UV-1800 spectrophotometer (Kyoto, Japan) and Agilent G9800A fluorescence spectrophotometer (Santa Clara, CA, USA) in DMSO, respectively. As is known, concentration has an effect on such measurements [49,50], and it was kept at 5 µg/mL in the present work. Fourier-transform infrared (FT-IR) spectra were recorded using a Bruker Tensor II FT-IR spectrophotometer (Ettlingen, Germany).…”

Section: Characterizationmentioning

confidence: 99%

Graphene Oxide/Cholesterol-Substituted Zinc Phthalocyanine Composites with Enhanced Photodynamic Therapy Properties

Erden

2023

Materials

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In the present work, cholesterol (Chol)-substituted zinc phthalocyanine (Chol-ZnPc) and its composite with graphene oxide (GO) were prepared for photodynamic therapy (PDT) applications. Briefly, Chol-substituted phthalonitrile (Chol-phthalonitrile) was synthesized first through the substitution of Chol to the phthalonitrile group over the oxygen bridge. Then, Chol-ZnPc was synthesized by a tetramerization reaction of Chol-phthalonitrile with ZnCl2 in a basic medium. Following this, GO was introduced to Chol-ZnPc, and the successful preparation of the samples was verified through FT-IR, UV–Vis, 1H-NMR, MALDI-TOF MS, SEM, and elemental analysis. Regarding PDT properties, we report that Chol-ZnPc exhibited a singlet oxygen quantum yield (Φ∆) of 0.54, which is slightly lower than unsubstituted ZnPc. Upon introduction of GO, the GO/Chol-ZnPc composite exhibited a higher Φ∆, about 0.78, than that of unsubstituted ZnPc. Moreover, this enhancement was realized with a simultaneous improvement in fluorescence quantum yield (ΦF) to 0.36. In addition, DPPH results suggest low antioxidant activity in the composite despite the presence of GO. Overall, GO/Chol-ZnPc might provide combined benefits for PDT, particularly in terms of image guidance and singlet oxygen generation.

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Section: Characterizationmentioning

confidence: 99%