Effect of the route of administration of methylprednisolone on oedema and trismus in impacted lower third molar surgery

Koçer, Gülperi; Yüce, Esra; Öncül, Ayşegül Tüzüner; Dereci, Ömür; Koşkan, Özgür

doi:10.1016/j.ijom.2013.11.005

Cited by 35 publications

(40 citation statements)

References 11 publications

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“…Facial swelling, pain and trismus are well‐known sequelae caused by the physiological inflammatory response to the surgical trauma . Various pharmacological and therapeutic methods including non‐steroidal anti‐inflammatory drugs, corticosteroids, surgical drains, local compression and low‐level laser therapy are often used to suppress the inflammatory response after SRM3, and the outcome has been documented in systematic reviews and meta‐analyses …”

Section: Introductionmentioning

confidence: 99%

Therapeutic efficacy of cryotherapy on facial swelling, pain, trismus and quality of life after surgical removal of mandibular third molars: A systematic review

Larsen

Kofod

Starch‐Jensen

2019

J of Oral Rehabilitation

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The objective was to test the hypothesis of no difference in facial swelling, pain, trismus and immediate quality of life after surgical removal of mandibular third molars, with or without post-operative cryotherapy. A MEDLINE (PubMed), EMBASE database and Cochrane library search in combination with a hand search of relevant journals were conducted by including human randomised controlled trials published in English until 17 July 2018. The search identified 37 titles. Six studies with low or unclear risk of bias fulfilled the inclusion criteria. Intermittent cryotherapy for 30 minutes during the first post-operative days significantly diminished facial swelling, pain and trismus compared with no cryotherapy. Patient's satisfaction and perception of recovery were significantly increased with cryotherapy. Therapeutic efficacy of intermittent cryotherapy on post-operative facial swelling, pain and trismus seems to be improved compared with continuous cryotherapy. Considerable variations in study design, diversity of used evaluation methods, outcome measures and various methodological confounding factors posed serious restrictions to review the literature in a quantitative systematic manner. Thus, conclusions drawn from the results of this systematic review should be interpreted with caution. Further well-designed randomised controlled trials including standardised protocol, larger patient sample, blinded outcome assessors, patient-reported outcome measures and three-dimensional volumetric analysis of facial swelling are required before evidence-based recommendations can be provided. K E Y W O R D S cryotherapy, dentistry, mandible, pain, review, third molar, trismus

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Section: Introductionmentioning

confidence: 99%

Therapeutic efficacy of cryotherapy on facial swelling, pain, trismus and quality of life after surgical removal of mandibular third molars: A systematic review

Larsen

Kofod

Starch‐Jensen

2019

J of Oral Rehabilitation

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“…Trismus as a postoperative predicted complication can be prevented by several means as the use of corticosteroids, non-steroidal anti-inflammatory, cold packs over the traumatized areas or laser therapy [2][3][4]. Hence, even if no therapy can be predicted prior to the occurrence of a facial fracture, these alternatives seem logical during the perioperative period to improve TMJ recovery.…”

Section: Discussionmentioning

confidence: 99%

The effect of facial fractures on mouth opening range: a case series

Borba¹,

Porto²,

Santini³

et al. 2018

RSBO

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Introduction: Facial fractures can result in limitation of mouth opening range, which consequently leads to functional impairments. Objective: To identify the influence of facial fractures and their corrective surgery on mouth opening range. Material and methods: Consecutive patients submitted to maxillofacial surgery had their mouth opening range measured at four different moments: preoperative (T0), immediate post-operative (within 24 hours after operation) (T1), one-week post-operative (T2) and one-month postoperative (T3). Eighteen subjects composed the sample, majorly represented by male gender, fractures caused by direct trauma as in traffic accidents, age among 21-30 years old and presenting mandible fracture. Results: Mouth opening at T0 demonstrated a mean value of 26.63 mm, T1 decreased to a mean of 22.59 mm, T2 mean value evolved to 26.42 mm and T3 displayed mean value of 34.57 mm. Statistical evaluation demonstrated overall significance for the comparison among all different periods, particularly for isolated mandible fractures, except between T0 and T2. Conclusion: It can be suggested that fracture itself and surgery for its correction have a negative effect on mouth opening range; however, the capacity of mouth opening presents signs of recovery since the first post-operative week, with notable progression until one month after surgery.

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“…Quanto à redução do edema, Kocer et al (28) relatam a administração de injeção de dexametasona no músculo masseter obtendo um resultado satisfatório se comparado a outras vias de administração do fármaco, como por exemplo a via oral. Essa redução se dá em virtude do processo farmacodinâmico, onde na administração enteral o fármaco necessita passar por todo o trato gastrointestinal, em contrapartida, na via parenteral há a deposição do medicamento diretamente no local da inflamação.…”

Section: Corticosteroides No Controle Da Dor E Edemaunclassified

“…(30) Em um estudo duplo-cego cruzado realizado por Calvo et al (30) em que foram feitas exodontias de terceiros molares inferiores bilateralmente medicando os pacientes no pós-operatório com AINEs inibidores seletivos da COX-2 (etoricoxib 120mg) e AINEs convencionais (Ibuprofeno 600mg), os resultados não apresentaram diferenças em relação ao controle da dor pós--operatória. (28) Após a remoção cirúrgica de terceiros molares, o curso pós-operatório é caracterizado por dor e edema afetando vários graus na qualidade de vida do paciente. "Esta lesão de tecidos provoca a liberação da ciclooxigense-2, que induz a atividade de prostaglandinas que sensibilizam nociceptores periféricos e induzem sintomas da inflamação".…”

Section: Anti-inflamatórios Não Esteroidais No Controle Da Dor E Do Eunclassified

O Uso De Antiinflamatórios Esteroidais E Não Esteriodais No Controle Da Dor E Do Edema Em Cirurgia De Terceiros Molares

Silva

Pereira

2016

J Dent Pub H

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Introduction: Third molars are the last teeth to erupt through the oral cavity and in some cases they are congenitally missing, display impaction or remain included. There are many reasons for their removal: decay, lack of space in the dental arch or problems during its eruption. During surgical extraction, oral tissues may be injured, which causes painful symptoms and edema. To combat these surgical complications, it is necessary the use of drugs that fight inflammation, non-steroidal anti-inflammatory drug (NSAIDs) and corticosteroids. To obtain best results, the combination of NSAIDs and steroidal anti-inflammatory drugs are used in patients, either as preemptive medication and as postoperative medication. Objective: Performing a literature review in order to determine which drug classes have better postoperative outcomes for pain and swelling in of third molars extraction. Materials and methods: Studies present in SciELO, Lilacs and Pubmed databases published between 2000-2014 were included. Final considerations: Corticosteroids are used preemptively in order to reduce swelling frame, while NSAIDs have greater use in the postoperative period, in an attempt to reduce the pain.

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Effect of the route of administration of methylprednisolone on oedema and trismus in impacted lower third molar surgery

Cited by 35 publications

References 11 publications

Therapeutic efficacy of cryotherapy on facial swelling, pain, trismus and quality of life after surgical removal of mandibular third molars: A systematic review

Therapeutic efficacy of cryotherapy on facial swelling, pain, trismus and quality of life after surgical removal of mandibular third molars: A systematic review

The effect of facial fractures on mouth opening range: a case series

O Uso De Antiinflamatórios Esteroidais E Não Esteriodais No Controle Da Dor E Do Edema Em Cirurgia De Terceiros Molares

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