Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose: An in vitro release study

Lopez-Polo, Johana; Soto, Andrea; Zamorano, Marcela; Silva-Weiss, Andrea; Oyarzun-Ampuero, Felipe A.; Brossard, Natalia; Fuentes, Jocelyn; Osorio, Fernando A.

doi:10.1016/j.lwt.2023.115583

Cited by 5 publications

(1 citation statement)

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“…Finally, the antioxidant activity values obtained for the TLS sample are similar to those previously reported for nanoliposomes made with quercetin and liposomes made with hemp seed oil [51,52]. The complex interplay between liposomal encapsulation, multilamellarity associated with ultrasound cycles, and antioxidant activity of tannins highlights the need for comprehensive evaluation when designing nanoliposome delivery systems for antioxidant compounds, providing a solid foundation for future research and practical applications in the development of efficient delivery strategies for bioactive compounds with antioxidant properties.…”

Section: Antioxidant Activitysupporting

confidence: 82%

Physicochemical Properties of Nanoliposomes Encapsulating Grape Seed Tannins Formed with Ultrasound Cycles

Monasterio,

Osorio

2024

Foods

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Grape seeds are an excellent source of flavonoids and tannins with powerful antioxidant properties. However, the astringency of tannins limits their direct incorporation into food. To overcome this challenge, we investigated the encapsulation of grape seed tannins within nanoliposomes formed by ultrasound cycling. We characterized the nanoliposomes’ physicochemical properties, including encapsulation efficiency, antioxidant activity, stability, microstructure, and rheological properties. Our findings reveal that the nanoliposomes exhibited excellent stability under refrigerated conditions for up to 90 days with a mean particle size of 228 ± 26 nm, a polydispersity index of 0.598 ± 0.087, and a zeta potential of −41.6 ± 1.30 mV, maintaining a spherical multilamellar microstructure. Moreover, they displayed high antioxidant activity, with encapsulation efficiencies of 79% for epicatechin and 90% for catechin. This innovative approach demonstrates the potential of using ultrasound-assisted nanoliposome encapsulation to directly incorporate grape seed tannins into food matrices, providing a sustainable and efficient method for enhancing their bioavailability and functionality.

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Section: Antioxidant Activitysupporting

confidence: 82%