Effect of the dental adhesive, 4‐META/MMA‐TBB resin, on adhesion and keratinization of regenerating oral epithelium

Abstract

Backgroundand Objective: The 4-META/MMA-TBB (4-(2-methacryloxyethyl)trimellitic

Application of 4-META/MMA-TBB resin for fixation of membrane to tooth in guided tissue regeneration in dog

“…This lends support to the previously reported characteristics of 4-META/MMA-TBB resin as being a biocompatible material which adheres to metal, enamel and dentin that can be applied safely to the vital tooth 24) . It seems likely that 4-META/MMA-TBB resin induced less tissue irritation in the newly formed gingival tissue in this study, which is compatible with the results of Tsuchiya et al 23) demonstrating that 4-META/MMA-TBB resin covered the wound by adherence with laminins and integrins in the initial process of epithelial regeneration.…”

“…Generally, when applied to promote membrane fixation to tooth, 4-META/MMA-TBB resin is polymerized at the connective tissue interface before deep infiltration of monomers via blood or saliva, creating a space for subsequent epithelial tissue regeneration between the resin and connective tissue 23) . Our results showed no clear inflammatory reaction in the regenerated periodontal tissue.…”

The junctional epithelium originates from the odontogenic epithelium of an erupted tooth

“…However, the source of these cells is unclear, and determining whether the JE is replaced by the oral epithelium is difficult3839. To clarify whether the JE is maintained as the odontogenic epithelium or replaced by the oral epithelium, the re-formation of the JE following gingivectomy has been studied2540414243. However, in the gingivectomy model, neglecting the existence of residual JE is difficult.…”

Effect of the Topical Use of the Antioxidant Taurine on the Two Basement Membrane Proteins of Regenerating Oral Gingival Epithelium

“…The expression of laminin 5 at the front margin of regenerating epithelium at 1 and 3 days postgingivectomy was demonstrated 33 . In another study, intense expression of laminin γ2, which is the major component of laminin 5, was shown in basal cells of both oral epithelium and at the tooth surface and in connective tissues at 3 to 5 days post‐surgery 15 .…”