Effect of the Commercial Mixed Live Newcastle Disease and Infectious Bronchitis Vaccines and the Use of Two Separate Vaccines Given Simultaneously on Systemic Antibody Responses

Mayahi, M; Talazadeh, Forough; Aslahi, Hamid

doi:10.21859/isv.7.3.17

Cited by 5 publications

(9 citation statements)

References 5 publications

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“…The outcome of infection and interaction between the two viral and one bacterial strain indicated that there is no potential interference with the replication of the pathogenic strains. Mayahi et al (2013) showed that the use of polyvalent vaccines combined in the manufacturing laboratory can attenuate the interference between these viruses when compared to vaccines associated just before vaccination. The trial compared that chicks received the conventional vaccines (group one) and combined vaccine (group two and three); group three provided best antibody response.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the safety and efficacy of combined Newcastle disease, fowl pox and fowl typhoid vaccine under laboratory condition

Tadesse¹,

Belete²,

Deressa³

2018

J. Vet. Med. Anim. Health

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An experimental study was conducted on day-old chicks to evaluate the safety and efficacy of combined Newcastle diseases (ND), fowl pox (FP) and fowl typhoid (FT) vaccine. The vaccine was prepared using the Lasota strain of Newcastle disease virus (NDV), the FP strain of fowl pox virus (FPV) and the 9R strain of FT. The vaccine was found safe, as no clinical signs or mortalities were observed. Post vaccination Haemaglutination Inhibition (HI) titre for ND was above the required protection level (≥1:16) and its geometric means (GM) were 0.0098, 0.0063 and 0.0059 for group one, two and three respectively, who received conventional and combined vaccine. The difference in GM between the three vaccinated groups were not significant (p=0.544). The trivalent combined vaccine did not show significant difference in the HI titre result among the groups that were given conventional vaccines and the other two experimental groups which received trivalent vaccine (p=0.257). From 75 samples, 73 (97.3%) were positive for FT through rapid slide agglutination test (RSAT). The chicks were challenged separately for the three diseases using the specific pathogens. Both combined and conventional vaccine conferred protection upon challenge. For ND challenge, 93.3% (n=14/15) of the control groups died. From FT and FP control groups 86.6% (n=13/15) and 20% (n=3/15) respectively died up on challenge. Both combined and conventional vaccine type conferred a similar and good level of protection. However, the use of combined vaccine has considerable advantage particularly in terms of convenience and cost effectiveness to control multiple diseases through simple immunization schedule. Further studies were recommended on the development of combined avian vaccines in Ethiopia.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the safety and efficacy of combined Newcastle disease, fowl pox and fowl typhoid vaccine under laboratory condition

Tadesse¹,

Belete²,

Deressa³

2018

J. Vet. Med. Anim. Health

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“…In some countries, this has caused “super-crowded” vaccination schedules, resulting in frequent vaccinations and bird handling. For live viral vaccines, few studies have highlighted compatibility of co-administering NDV, IBV strains, and aMPV simultaneously (84,85), NDV and IBV (86), and NDV and IBD vaccines (87) within defined geographical regions. It is important to note that different combinations of live vaccines are required to combat different pathogens globally, which varies for different countries.…”

Section: Challenges With Use Of Live Viral Vaccinesmentioning

confidence: 99%

Pros and Cons on Use of Live Viral Vaccines in Commercial Chicken Flocks

Ganapathy,

Parthiban

2023

Avian Diseases

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“…In 2016, Mayahi et al investigated the clinical efficacy of two commercial intermediate vaccines against IBD manufactured by Razi Vaccine and Serum Research Institute (RVSI) of Iran and Lohmann Company (Germany) (31). In this study, the exact time of vaccination in chickens was determined using Deventer's formula.…”

Section: Vaccine Related Studiesmentioning

confidence: 99%

A review of the Infectious Bursal Disease (IBD) in Iran

Salavati,

Peighambari

2023

J Poult Sci Avian Dis

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Infectious bursal disease (IBD) is one of the most important diseases in the poultry industry all over the world. It is a viral disease caused by a birnavirus, which weakens the immune system. The disease was observed for the first time in 1962 in the Gumboro area of Delaware, USA. The first report of this disease in Iran dates back to 1994. Since then, various investigations have been conducted in Iran on the isolation and identification of IBDV isolates, cognitive immunological studies and vaccine testing and design, disease pathogenesis and pathology, and recently in the field of genetic engineering. The main procedure for IBD control is vaccination in productive and commercial herds. Therefore, studies related to vaccination and immunogenicity play an essential role in designing preventive measures against this disease. In this manuscript, a comprehensive review of the studies conducted in Iran on IBD has been discussed.

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Effect of the Commercial Mixed Live Newcastle Disease and Infectious Bronchitis Vaccines and the Use of Two Separate Vaccines Given Simultaneously on Systemic Antibody Responses

Cited by 5 publications

References 5 publications

Evaluation of the safety and efficacy of combined Newcastle disease, fowl pox and fowl typhoid vaccine under laboratory condition

Evaluation of the safety and efficacy of combined Newcastle disease, fowl pox and fowl typhoid vaccine under laboratory condition

Pros and Cons on Use of Live Viral Vaccines in Commercial Chicken Flocks

A review of the Infectious Bursal Disease (IBD) in Iran

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