“…Among them degradation of DDT has been correlated with DDT-dehydrochlorinase (Abedi et al, 1963) whereas degradation of other organochlorines has been correlated with this enzyme and oxidases (Sternberg and Kearns, 1950;Kimura and Brown, 1964;Oppenoorth and House, 1968). Degradation of organophosphates and carbamates has been correlated with general esterases, carboxyesterases, cholinesterases and mixed function oxidases (Rashan et al,1979;Naqviet al, 1984;Naqvi and Rub, 1985;Jagadeesan, 2011) In the present study esterases (acid phosphatae, alkaline phosphatase and cholinesterase) and oxidase (LDH, ICDH,GOT, GPT) and other enzymes have been determined in the Phosphine treated and un-treated 6 th instar larvae of Trogoderma granarium to find any correlation or toxic effect of Phosphine with induction / inhibition of enzymes. Tables 1 and 2 show the changes in the activities of various enzymes (AcP, AkP, amylase, ALAT, ASAT, LDH, ICDH, ChE, protease, aminopeptidase, trehalase) in 6 th instar larvae of T. granariumin two different populations Lhr and Khw collected from different godowns of Punjab have been quantified after the exposure of Phosphine for 20 h. The results of present study suggested that almost all the enzymes were found to be sensitive to Phosphine.…”