Effect of temperature on sulfonamide antibiotics degradation, and on antibiotic resistance determinants and hosts in animal manures

Lin, Hui; Zhang, Jin; Chen, Hongjin; Wang, Jianmei; Sun, Wanchun; Zhang, Xin; Yang, Yuyi; Wang, Qiang; Ma, Junwei

doi:10.1016/j.scitotenv.2017.07.057

Cited by 92 publications

(23 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, sulfonamide removal is more important in swine manure than chicken manure. In addition, sulfonamide transformation could be more pronounced in chicken manure at 30°C rather than 60°C [96]. These results suggested that the microbial community composition, related to the 10 and 20 mg kg -1 dry matter) showed that chortetracycline and sulfamethazine removal depends on the presence of straw but tylosine removal did not [98].…”

mentioning

confidence: 86%

Human and veterinary antibiotics during composting of sludge or manure: Global perspectives on persistence, degradation, and resistance genes

Ezzariai

Hafidi

Khadra

et al. 2018

Journal of Hazardous Materials

327

111

View full text Add to dashboard Cite

Wastewater treatment plant effluent, sludge and manure are the main sources of contamination by antibiotics in the whole environment compartments (soil, sediment, surface and underground water). One of the major consequences of the antibiotics discharge into the environment could be the prevalence of a bacterial resistance to antibiotic. In this review, four groups of antibiotics (Tetracyclines, Fluoroquinolones, Macrolides and Sulfonamides) were focused for the background on their wide spread occurrence in sludge and manure and for their effects on several target and non-target species. The antibiotics concentrations range between 1 and 136,000 μg kg of dry matter in sludge and manure, representing a potential risk for the human health and the environment. Composting of sludge or manure is a well-known and used organic matter stabilization technology, which could be effective in reducing the antibiotics levels as well as the antibiotic resistance genes. During sludge or manure composting, the antibiotics removals range between 17-100%. The deduced calculated half-lives range between 1-105 days for most of the studied antibiotics. Nevertheless, these removals are often based on the measurement of concentration without considering the matter removal (lack of matter balance) and very few studies are emphasized on the removal mechanisms (biotic/abiotic, bound residues formation) and the potential presence of more or less hazardous transformation products. The results from the few studies on the fate of the antibiotic resistance genes during sludge or manure composting are still inconsistent showing either decrease or increase of their concentration in the final product. Whether for antibiotic or antibiotic resistance genes, additional researches are needed, gathering chemical, microbiological and toxicological data to better understand the implied removal mechanisms (chemical, physical and biological), the interactions between both components and the environmental matrices (organic, inorganic bearing phases) and how composting process could be optimized to reduce the discharge of antibiotics and antibiotic resistance genes into the environment.

show abstract

mentioning

confidence: 86%

Human and veterinary antibiotics during composting of sludge or manure: Global perspectives on persistence, degradation, and resistance genes

Ezzariai

Hafidi

Khadra

et al. 2018

Journal of Hazardous Materials

327

111

View full text Add to dashboard Cite

show abstract

“…Approximately 100 mg of organic fertilizer samples was used to determine their C, H, O, N, and S contents and C/N ratios by means of an elemental analyzer (vario MACRO cube, Elementar, Germany) [28]. The antibiotic residues were determined by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS, Thermo Fisher Scientific, Waltham, USA) analysis, and extraction and purification procedures followed the description by Qian et al [29,30] Nine different antibiotics were analyzed: SDZ, SMZ, SMN, OTC, TC, CTC, Dox, Oflox, and Enroflox. In this experiment, according to the parameters of the test instrument, the detection limit was in the range of 0.5-15 µg kg −1 manure (dry weight), and the limit of quantification was in the range of 1.5-50 µg kg −1 manure (dry weight) [29].…”

Section: Analysis Of Physicochemical Properties and Antibiotic Residuesmentioning

confidence: 99%

Effects of Composting Different Types of Organic Fertilizer on the Microbial Community Structure and Antibiotic Resistance Genes

Zhou

Yao

2020

Microorganisms

View full text Add to dashboard Cite

Organic fertilizer is a major carrier that stores and transmits antibiotic resistance genes (ARGs). In the environment, due to the application of organic fertilizers in agriculture, the increasing diversity and abundance of ARGs poses a potential threat to human health and environmental safety. In this paper, the microbial community structure and ARGs in different types of organic fertilizer treated with composting were examined. We found that the abundance and diversity of ARGs in earthworm cast organic fertilizer were the lowest and the highest in chicken manure organic fertilizer. Interestingly, the abundance and diversity of ARGs, especially beta-lactam resistance genes, sulfonamide resistance genes, and macrolide-lincosamide-streptogramin B (MLSB) resistance genes, in organic fertilizers were reduced significantly, while composting caused no significant change in mobile genetic elements (MGEs), where antibiotic deactivation and the use of efflux pumps were the two most dominant mechanisms. It was clear that removal of ARGs became more efficient with increasing reduction in the bacterial abundances and diversity of potential ARG hosts, and integron-mediated horizontal gene transfers (HGTs) played an important role in the proliferation of most ARG types. Therefore, the reduction in ARGs was mainly driven by changes in bacterial community composition caused by composting. Furthermore, rather than HGTs, the diversity and abundance of bacterial communities affected by compost physical and chemical properties were the main drivers shaping and altering the abundance and diversity of ARGs, which was indicated by a correlation analysis of these properties, antibiotic residues, microbial community structure, and ARGs. In general, high-temperature composting effectively removed antibiotic residues and ARGs from these organic fertilizers; however, it cannot prevent the proliferation of MGEs. The insights gained from these results may be of assistance in the safe and rational use of organic fertilizers by indicating the changes in microbial community structure and ARGs in different types of organic fertilizer treated with composting.

show abstract

“…While the TET-resistant subcommunities in the control soil were represented by a few taxa dominated by Dyella , the manure-soil interface harboured a rich TET-resistant bacteriome dominated by Providencia and Enteroccoccus in the case of native soils, and by Providencia and Achromobacter in the case of γ-irradiated soils, already 7 days after addition. These genera have been frequently found in cow and pig manure and may harbour TET-r genes such as tet (W), tet (Q) or tet (M) 31–34 . While high levels of TET-r genes persisted in soil over the whole incubation period, the composition of TET-resistant subcommunities partially reverted at the end of the experiment.…”

Section: Discussionmentioning

confidence: 99%

Native soil microorganisms hinder the soil enrichment with antibiotic resistance genes following manure applications

Pérez-Valera

Kyselková

Ahmed

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Bacterial genes responsible for resistance to antibiotic agents (ARG) are spread from livestock to soil through application of manure, threatening environmental and human health. We investigated the mechanisms of ARG dissemination and persistence to disentangle i) the influence of nutrients and microorganisms on the soil tetracycline (TET) resistome, and ii) the role of indigenous soil microbiota in preventing ARG spread. We analysed short-term (7 days) and persistent (84 days) effects of manure on the resistome of three antibiotic-free pasture soils. Four microcosm treatments were evaluated: control, mineral nutrient fertilization, and deposition of a layer of fresh manure onto soil or γ-irradiated soil. We quantified five TET-resistance genes, isolated 135 TET-resistant bacteria and sequenced both culturable TET-resistant and whole bacterial communities. Manure amendments, but not nutrient addition, increased the abundance of TET-r genes such as tet (Y). Such changes persisted with time, in contrast with the TET-resistant bacterial composition, which partially recovered after manure amendments. Manured γ-irradiated soils showed significantly lower nutrient content and higher TET-r gene abundance than non-irradiated soils, suggesting that native soil bacteria are essential for the fertilization effect of manure on soil as well as control the dissemination of potentially risky TET-r genes.

show abstract

Effect of temperature on sulfonamide antibiotics degradation, and on antibiotic resistance determinants and hosts in animal manures

Cited by 92 publications

References 37 publications

Human and veterinary antibiotics during composting of sludge or manure: Global perspectives on persistence, degradation, and resistance genes

Human and veterinary antibiotics during composting of sludge or manure: Global perspectives on persistence, degradation, and resistance genes

Effects of Composting Different Types of Organic Fertilizer on the Microbial Community Structure and Antibiotic Resistance Genes

Native soil microorganisms hinder the soil enrichment with antibiotic resistance genes following manure applications

Contact Info

Product

Resources

About