Effect of Temperature on Eversporting Eye Color in Drosophila Melanogaster

Gowen, John W.; Gay, E. H.

doi:10.1126/science.77.1995.312

Cited by 46 publications

(21 citation statements)

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“…In strain sc 8 , where variegation affects bristles, heterochromatization is depressed by temperatures either lower or higher than normal (Prokofieva-Belgovskaya, 1947). Gowen & Gay (1933) demonstrated that low temperatures enhance mottling of the eyes. Chen (1948) found that in mottledeye strains temperature is effective during the pupal stage, and these results were confirmed by Becker (1960Becker ( , 1961.…”

Section: Introductionmentioning

confidence: 97%

On the relationship between heterochromatization and variegation inDrosophila, with special reference to temperature sensitive periods

Hartmann-Goldstein

1967

Genet. Res.

105

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Using a strain of D. melanogaster carrying an X-4 translocation, comparison between groups of individuals cultured at 14°, 19° and 25°C. showed good correlation between heterochromatization, variegation in malpighian tubules and Notch. All these phenomena are enhanced by low temperatures. Correlation was less good within each temperature group, and considerable variability was observed between individuals within the group, and between nuclei from one individual.Experiments involving a temperature change during the embryonic period indicate that (1) heterochromatization is especially temperature-sensitive during the early embryonic period but may be increased by low temperature later, (2) larval malpighian tubules are sensitive to temperature only during the early embryonic stage, and (3) N is influenced by temperature during early embryonic life and also during the larval period.Our observations, in conjunction with those of other workers, could be explained as follows: exposure of individuals to low temperature at a time when a specific system is beginning to differentiate will cause the processes concerned to be blocked in some cells. At least during the early embryonic stages this appears to involve heterochromatization of the relevant locus. Once the processes are established which will lead to the formation of a character, further heterochromatization has no effect on the phenotype. Temperature may affect pupal or adult phenotype in this way or by a direct action on the metabolic processes of cells.Further experiments showed: (1) the greatest temperature-sensitivity of all three phenomena within the first 6 hours of embryonic life; (2) striking fluctuations of the effect of temperature, especially within the early embryonic period; (3) close correspondence between all three phenomena in time of response to temperature. Some alternative interpretations are considered.

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Section: Introductionmentioning

confidence: 97%

On the relationship between heterochromatization and variegation inDrosophila, with special reference to temperature sensitive periods

Hartmann-Goldstein

1967

Genet. Res.

105

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“…Early Drosophila work demonstrated the temperature sensitivity of two classic chromatin-related phenotypes-position-effect variegation (PEV) (Gowen 1933) and polytene chromosome ''puff'' induction (Ashburner 1967). More recent studies demonstrate that silencing maintained by the Polycomb group genes (PcGs), which remodel chromatin at developmentally important loci to maintain developmental trajectories (Lewis 1978;Schwartz and Pirrotta 2007), increases with increasing temperature (Fauvarque and Dura 1993).…”

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confidence: 99%

Evidence of Spatially Varying Selection Acting on Four Chromatin-Remodeling Loci in Drosophila melanogaster

Levine

Begun

2008

Genetics

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The packaging of DNA into proper chromatin structure contributes to transcriptional regulation. This packaging is environment sensitive, yet its role in adaptation to novel environmental conditions is completely unknown. We set out to identify candidate chromatin-remodeling loci that are differentiated between tropical and temperate populations in Drosophila melanogaster, an ancestrally equatorial African species that has recently colonized temperate environments around the world. Here we describe sequence variation at seven such chromatin-remodeling loci, four of which (chd1, ssrp, chm, and glu) exhibit strong differentiation between tropical and temperate populations. An in-depth analysis of chm revealed sequence differentiation restricted to a small portion of the gene, as well as evidence of clinal variation along the east coasts of both the United States and Australia. The functions of chd1, chm, ssrp, and glu point to several novel hypotheses for the role of chromatin-based transcriptional regulation in adaptation to a novel environment. Specifically, both stress-induced transcription and developmental homeostasis emerge as potential functional targets of environment-dependent selection.

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“…The Drosophila melanogaster Y chromosome, which has both a long arm (YL) and a short arm (YS), is 12-18% longer than the X chromosome at metaphase (1,2). In contrast to the many genes localizd to the smaller X chromosome, very few genes have been identified on the Y chromosome.…”

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confidence: 99%

A fertility region on the Y chromosome of Drosophila melanogaster encodes a dynein microtubule motor.

Gepner

Hays

1993

Proc. Natl. Acad. Sci. U.S.A.

101

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Effect of Temperature on Eversporting Eye Color in Drosophila Melanogaster

Cited by 46 publications

References 0 publications

On the relationship between heterochromatization and variegation inDrosophila, with special reference to temperature sensitive periods

On the relationship between heterochromatization and variegation inDrosophila, with special reference to temperature sensitive periods

Evidence of Spatially Varying Selection Acting on Four Chromatin-Remodeling Loci in Drosophila melanogaster

A fertility region on the Y chromosome of Drosophila melanogaster encodes a dynein microtubule motor.

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