Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality

Howatson, Glyn; Bell, Phillip G.; Tallent, Jamie; Middleton, Benita; McHugh, Malachy P.; Ellis, Jason

doi:10.1007/s00394-011-0263-7

Cited by 181 publications

(169 citation statements)

References 25 publications

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“…The consumption of 8 ounces of tart cherry juice in the morning and nighttime for 2 wk was associated with a significant reduction in insomnia severity and WASO in adults with chronic insomnia (43). Howatson et al (45) later replicated the study in a population of young, healthy adults. One week of tart cherry juice supplementation increased urinary melatonin concentrations, TST, and SE compared with a placebo juice.…”

Section: Sleep-promoting Foods and Sleep Quality: Experimental Findingsmentioning

confidence: 94%

Effects of Diet on Sleep Quality

St‐Onge

Mikic

Pietrolungo

2016

Advances in Nutrition

387

300

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There is much emerging information surrounding the impact of sleep duration and quality on food choice and consumption in both children and adults. However, less attention has been paid to the effects of dietary patterns and specific foods on nighttime sleep. Early studies have shown that certain dietary patterns may affect not only daytime alertness but also nighttime sleep. In this review, we surveyed the literature to describe the role of food consumption on sleep. Research has focused on the effects of mixed meal patterns, such as high-carbohydrate plus lowfat or low-carbohydrate diets, over the short term on sleep. Such studies highlight a potential effect of macronutrient intakes on sleep variables, particularly alterations in slow wave sleep and rapid eye movement sleep with changes in carbohydrate and fat intakes. Other studies instead examined the intake of specific foods, consumed at a fixed time relative to sleep, on sleep architecture and quality. Those foods, specifically milk, fatty fish, tart cherry juice, and kiwifruit, are reviewed here. Studies provide some evidence for a role of certain dietary patterns and foods in the promotion of high-quality sleep, but more studies are necessary to confirm those preliminary findings. Adv Nutr 2016;7:938-49.

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Section: Sleep-promoting Foods and Sleep Quality: Experimental Findingsmentioning

confidence: 94%

Effects of Diet on Sleep Quality

St‐Onge

Mikic

Pietrolungo

2016

Advances in Nutrition

387

300

View full text Add to dashboard Cite

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“…following exercise [9] and improve sleep quality [10,11]. Despite previous studies in cell culture and animal 40 models, where cherry extracts have been shown to exert a range of cardio-protective effects [12,5], there has…”

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confidence: 99%

Phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of phenolic acids on vascular smooth muscle cells in vitro

et al. 2015

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“…16 In fact, cherry concentrate, containing 85 µg of melatonin, increased 6-sulphatoximelatonin levels in urine by 17%. 17 Drinking 400 mL per day of a "stabilized" grape juice also elevated the 6-sulphatoximelatonin concentration in urine. 18 Serum melatonin is rapidly hydroxylated to 6-sulphatoximelatonin in the liver, is excreted by the kidneys, and has a half-life of approximately 30 minutes.…”

Section: Melatonin Content In the Human Bodymentioning

confidence: 97%

Melatonin and its use in atherosclerosis and dyslipidemia

Danilenko¹,

Ragino²

2013

CPT

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A review of pineal melatonin synthesis, regulation, and physiological effects indicates that not only does melatonin act as a hormonal signal of darkness, but also that it possesses antioxidant and anti-inflammatory properties. Although oxidation and inflammation play a pivotal role in atherogenesis, no studies have investigated administration of melatonin for human arterial atherosclerosis. However, 13 clinical trials have investigated use of melatonin in dyslipidemia, which is a close correlate of atherosclerosis. The results of these clinical trials, particularly the five that are placebo-controlled, are inconclusive as to whether melatonin can normalize the blood lipid profile. Significant confounders in these studies might be a phase shift of the cholesterol rhythm by melatonin, a posture effect at venipuncture, uncontrolled diet during the course of melatonin intake, and the phenomenon of regression to the mean. Thus, future studies are required, which should also consider use of higher doses of melatonin and/or measurement of oxidized forms of cholesterol-containing particles (which are the most aggressive in relation to atherogenesis) in addition to lipidic fractions.

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Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality

Abstract: These data suggest that consumption of a tart cherry juice concentrate provides an increase in exogenous melatonin that is beneficial in improving sleep duration and quality in healthy men and women and might be of benefit in managing disturbed sleep.

Cited by 181 publications

References 25 publications

Effects of Diet on Sleep Quality

Effects of Diet on Sleep Quality

Phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of phenolic acids on vascular smooth muscle cells in vitro

Melatonin and its use in atherosclerosis and dyslipidemia

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