Effect of Tai Ji and/or Qigong on Patients with Stable Chronic Obstructive Pulmonary Disease A protocol for meta-analysis and systematic review

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a global health problem with high morbidity and mortality. Tai Ji and Qigong are traditional Chinese mediative movements, benefit COPD patient’s physical and mental health. Methods: We searched the following twelve databases Web of Science, EBSCO, Medline, EMBASE, Scopus, PubMed, PsycArticles, Psychology and Behavioral Sciences Collection, PsycInfo, CINAHL, Cochrane Library online and Clinical trials from inception to July 2023. Any RCTs managed with Tai Ji and/or Qigong on stable COPD were eligible without age, publishment language and comparison management restrict. Outcome measures comprised pulmonary function, the incidence of acute exacerbation, 6WMD, chronic pain, physical and/or cognitive function, and any assessment of people QoL. Results: Our research will update evidence summaries and provide a quantitative and standardized assessment of the effect of Tai Ji and/or Qigong on patients with stable COPD. Conclusion: Our research will generate the latest evidence for determining whether Tai Ji and/or Qigong is equivalent to conventional PR. Abbreviations: RCTs = randomized controlled trials; 6WMD = 6-minutes walking distance; QoL = quality of life; CIs = confidence intervals; CAT = COPD assessment test.

Effect of liuzijue qigong on patients with stable chronic obstructive pulmonary disease

“…All of the included trials described randomized allocation, and they were low risk in the fields of randomized allocation. Twelve studies were classified as having an unclear risk in the fields of allocation concealment [18][19][20][21][24][25][26][27][28][30][31][32] and one was high risk. [22] There was high risk of bias in the domain of blinding of participants and personnel, only 3 studies [23,29,33] used single-blind method, but no specific method of blinding was mentioned in these studies.…”

“…Only five of them were shown to blind their outcome assessment. [21,[23][24][32][33] All trials reported methods with a low risk of incomplete outcome data and 38 studies were at low risk of bias. With regard to selective outcome reporting bias, 10 studies were determined as low risk and the remaining were determined as unclear risk.…”

“…3). Eleven studies [21,[23][24][26][27][28][29][30][31][32][33] used FEV1% to assess the improvement of pulmonary function of COPD patients by LQG. The fixed effects model was conducted to incorporate the results, they had high heterogeneity (I 2 = 63%).…”

“…A total 16 studies [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] involving 1039 individuals were selected for this meta-analysis, 1 studies [23] were published in English, and 15 studies [18][19][20][21][22][24][25][26][27][28][29][30][31][32][33] were published in Chinese, six of which were dissertations. [24,[28][29][31][32][33] All eligible studies were published from 2008 to 2019. There were 13 studies with a sample size ≥40 participants, and the average age of participants is >60 years old.…”

“…The quality of each study was assessed using the Jadad scale, 5 studies were high-quality, [22][23]29,31,33] 10 studies were low-quality. [18][19][20][21][24][25][26][27][28]30,32] The basic characteristics of the included studies were shown in Table 1.…”