Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats

Kömürcü, Erkam; Özkan, Ömer Faruk; Kemik, Ahu Sarbay; Nusran, Gürdal; Aşık, Mehmet; Arslan, Emrah

doi:10.1016/j.jss.2013.11.1101

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…Besides the inflammatory status (Fortin et al, 2009;Suchitra et al, 2011), carnitine supplementation may have potential benefits in improving many common disorders, such as severe cardiovascular disorders (Ferrari et al, 2004), fat accumulation (Jang et al, 2014), renal disease (Fatouros et al, 2010) and diabetes (Kömürcü et al, 2014). Previous study showed that carnitine may be a protective factor against male infertility in severely infected patients (Abd-Allah et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Metabolomic profiles reveal key metabolic changes in heat stress-treated mouse Sertoli cells

Chen

et al. 2015

Toxicology in Vitro

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Section: Discussionmentioning

confidence: 99%

Metabolomic profiles reveal key metabolic changes in heat stress-treated mouse Sertoli cells

Chen

et al. 2015

Toxicology in Vitro

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“…8 Carnitine as an endogenous cofactor necessary for cellular reactions, has been considered by scientists as a kind of life boat in ischemic conditions. 9 , 10…”

Section: Discussionmentioning

confidence: 99%

The Effect of Topical Vitamin A and E on Ischemic Random Skin Flap Survival

Hassanpour

Rostami

Azargashb

et al. 2019

wjps

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BACKGROUND Ischemia of skin flaps is an important complication in reconstructive surgery. This study evaluated the efficacy of topical vitamins A and E on improving flap survival. METHODS Twenty-four white-albino male rats were randomly divided into two groups of treatment and control. Standard rectangular, distally based dorsal random pattern skin flap was elevated. Intra-peritoneal cephazoline was administered to prevent any unexpected infection. No pharmaceutical agent was administered for the control group, but pure vaseline ointment. In treatment group, vaseline plus vitamins A and E were administrated daily after surgery for 10 days. The rats were evaluated on the 10 th day after surgery for viable and necrotic portions of the flaps. RESULTS The mean values of necrosis in the flaps were 625±189.56 and 920.00±247.31 in the treatment and control groups, respectively. Vaseline plus vitamins increased flap survival significantly. CONCLUSION Topical vitamins A and E may be effective pharmaceutical agents to increase viability of random skin flaps in rats. They can be added to vasoactive topical agents to reach better results.

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Effect of systemic carnitine therapy on serum fibronectin level in diabetic rats

Cited by 2 publications

References 24 publications

Metabolomic profiles reveal key metabolic changes in heat stress-treated mouse Sertoli cells

Metabolomic profiles reveal key metabolic changes in heat stress-treated mouse Sertoli cells

The Effect of Topical Vitamin A and E on Ischemic Random Skin Flap Survival

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