Effect of surface mechanical attrition treatment on biodegradable Mg–1Ca alloy

Li, N.; Li, Y.D.; Li, Y.X.; Wu, Yuan-yuan; Zheng, Yufeng; Han, Yong

doi:10.1016/j.msec.2013.11.010

Cited by 71 publications

(62 citation statements)

References 35 publications

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“…Therefore, SMAT is considered as a promising strategy to enhance the mechanical strength of Mg based alloys when used as potential orthopedic implants. However, the corrosion resistance of SMATed metals is seriously impaired due to the increase of crystalline defects such as grain boundaries and dislocations 94. Supra‐Nano‐Dual‐Phase alloy membrane (SNDP) via magnetron sputtering is another novel surface treatment for Mg‐based metals, which can dramatically increase their mechanical strength close to the theoretical ideal strength for the potential use in high weight‐bearing skeletal sites 95.…”

Section: Novel Strategies For Modifying Mg‐based Orthopedic Implantsmentioning

confidence: 99%

Biodegradable Magnesium‐Based Implants in Orthopedics—A General Review and Perspectives

et al. 2020

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Biodegradable Mg‐based metals may be promising orthopedic implants for treating challenging bone diseases, attributed to their desirable mechanical and osteopromotive properties. This Review summarizes the current status and future research trends for Mg‐based orthopedic implants. First, the properties between Mg‐based implants and traditional orthopedic implants are compared on the following aspects: in vitro and in vivo degradation mechanisms of Mg‐based implants, peri‐implant bone responses, the fate of the degradation products, and the cellular and molecular mechanisms underlying the beneficial effects of Mg ions on osteogenesis. Then, the preclinical studies conducted at the low weight bearing sites of animals are introduced. The innovative strategies (for example, via designing Mg‐containing hybrid systems) are discussed to address the limitations of Mg‐based metals prior to their clinical applications at weight‐bearing sites. Finally, the available clinical studies are summarized and the challenges and perspectives of Mg‐based orthopedic implants are discussed. Taken together, the progress made on the development of Mg‐based implants in basic, translational, and clinical research has laid down a foundation for developing a new era in the treatment of challenging and prevalent bone diseases.

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Section: Novel Strategies For Modifying Mg‐based Orthopedic Implantsmentioning

confidence: 99%

Biodegradable Magnesium‐Based Implants in Orthopedics—A General Review and Perspectives

et al. 2020

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“…ECAP was reported to reduce localized corrosion through decreasing the size of the second phase particles and promoting microstructural homogeneity on ZK60 and pure Mg but showed a minor effect on the general corrosion resistance [36]. Surface mechanical attrition treatment (SMAT) applied to pure Mg and Mg-1Ca alloy, was reported to result in enhanced hardness and wettability but reduced corrosion resistance [37]. However, treatment of AZ91D magnesium alloys by SMAT resulted in contrasting results on corrosion behavior depending on processing parameters.…”

Section: Introductionmentioning

confidence: 99%

Effects of nanofeatures induced by severe shot peening (SSP) on mechanical, corrosion and cytocompatibility properties of magnesium alloy AZ31

et al. 2018

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The application of biodegradable magnesium-based materials in the biomedical field is highly restricted by their low fatigue strength and high corrosion rate in biological environments. Considering the sensitivity of both fatigue strength and corrosion rate to the surface characteristics of the material, apposite surface treatments could address these challenges. As a low cost and versatile severe plastic deformation technique aimed at inducing surface grain refinement, severe shot peening has been effective in enhancing mechanical properties and promoting cellular interactions on non-degradable biocompatible metallic materials. Herein, we treated the surface of a biocompatible magnesium alloy AZ31 by severe shot peening in order to evaluate the potential of surface grain refinement to enhance its functionality in a biological environment. The AZ31 samples were studied in terms of a wide variety of micro/nanostructural, mechanical, and chemical characteristics in addition to cytocompatibility properties. The evolution of surface grain structure and surface morphology were investigated using optical as well as scanning and transmission electron microscopy. Surface roughness, wettability and chemical composition, as well as in depth-microhardness and residual stress distribution, and corrosion resistance were investigated. Successive light surface grinding was used after severe shot peening to eliminate the effect of surface roughness and separately investigate the influence of grain refinement alone. Cytocompatibility tests with osteoblasts (or bone forming cells) were performed using sample extracts. Results revealed for the first time that severe shot peening can significantly enhance mechanical properties without causing adverse effects to the growth of surrounding osteoblasts. The corrosion behavior, on the other hand, was not improved by severe shot peening; nevertheless, slight grinding of the rough surface layer with a high density of crystallographic lattice defects, without removing the entire nanocrystallized layer, provided a good potential for improving corrosion characteristics after severe shot peening and thus, this method should be studied for a wide range of orthopedic applications in which biodegradable magnesium is used.

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“…Fig. 1 shows the research status of the three main body BM systems: Mg-based BMs [4,7,9,[25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42], Fe-based BMs [12,13,[43][44][45][46][47][48][49], and Zn-based BMs [15][16][17][50][51][52]. It is quite clear that among these BMs, Mg-based BMs [3][4][5][6][7][8][9] are the research's vanguard and main force with hundreds of publications on the in vitro cytoxicity, animal testing and clinical trails, Fe-based BMs [10][11][12][13] are reported in tens of publications on alloy design and several animal testing as potential vascular stent, Zn-based BMs …”

Section: Introductionmentioning

confidence: 99%

Progress of biodegradable metals

Zheng

Qin

2014

Progress in Natural Science: Materials International

354

160

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Biodegradable metals (BMs) are metals and alloys expected to corrode gradually in vivo, with an appropriate host response elicited by released corrosion products, then dissolve completely upon fulfilling the mission to assist with tissue healing with no implant residues. In the present review article, three classes of BMs have been systematically reviewed, including Mg-based, Fe-based and Zn-based BMs. Among the three BM systems, Mg-based BMs, which now have several systems reported the successful of clinical trial results, are considered the vanguards and main force. Fe-based BMs, with pure iron and Fe-Mn based alloys as the most promising, are still on the animal test stage. Zn-based BMs, supposed to have the degradation rate between the fast Mg-based BMs and the slow Fe-based BMs, are a rising star with only several reports and need much further research. The future research and development direction for the BMs are proposed, based on the clinical requirements on controllable degradation rate, prolonged mechanical stability and excellent biocompatibility, by optimization of alloy composition design, regulation on microstructure and mechanical properties, and following surface modification.

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Effect of surface mechanical attrition treatment on biodegradable Mg–1Ca alloy

Cited by 71 publications

References 35 publications

Biodegradable Magnesium‐Based Implants in Orthopedics—A General Review and Perspectives

Biodegradable Magnesium‐Based Implants in Orthopedics—A General Review and Perspectives

Effects of nanofeatures induced by severe shot peening (SSP) on mechanical, corrosion and cytocompatibility properties of magnesium alloy AZ31

Progress of biodegradable metals

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