Effect of sugar-sweetened beverages on body weight in children: design and baseline characteristics of the Double-blind, Randomized INtervention study in Kids

Ruyter, J.C. de; Olthof, Margreet R.; Kuijper, Lothar D. J.; Katan, Martijn B.

doi:10.1016/j.cct.2011.10.007

Cited by 34 publications

(52 citation statements)

References 50 publications

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“…The design of the study has been described previously. 20 The study started on November 14, 2009, and ended on July 22, 2011. We recruited children at eight elementary schools in an urban area near Amsterdam.…”

Section: Design and Study Populationmentioning

confidence: 99%

“…1). 20 Children in the same household received the same type of beverage, but they were unaware of this assignment.…”

Section: Design and Study Populationmentioning

confidence: 99%

“…We developed custom drinks for this study to ensure that the sugar-free and sugar-containing drinks tasted and looked essentially the same. 20 We hired Refresco Benelux to produce these beverages. The identical-looking 250-ml (8-oz) cans provided either 0 or 26 g of sucrose (0 or 104 kcal per day).…”

Section: Interventionmentioning

confidence: 99%

“…In addition, effectively blinded trials are important, because when investigators and participants know which treatment should cause weight loss, results may be biased. 20 We conducted the Double-blind, Randomized Intervention Study in Kids (DRINK) 20 to examine the effect on weight gain of masked replacement of sugar-sweetened beverages with noncaloric, artificially sweetened beverages. The double-blind design permitted the study of physiological mechanisms that were independent of behavioral cues and voluntary changes in consumption.…”

mentioning

confidence: 99%

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A Trial of Sugar-free or Sugar-Sweetened Beverages and Body Weight in Children

et al. 2012

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Section: Design and Study Populationmentioning

confidence: 99%

“…1). 20 Children in the same household received the same type of beverage, but they were unaware of this assignment.…”

Section: Design and Study Populationmentioning

confidence: 99%

Section: Interventionmentioning

confidence: 99%

mentioning

confidence: 99%

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A Trial of Sugar-free or Sugar-Sweetened Beverages and Body Weight in Children

et al. 2012

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“…Before the study was started, the precise design of the study was laid down in a study protocol published separately (De Ruyter et al 2012a). 7 This protocol stipulated exactly how the study would be executed, what measurements would be taken at what time, what statistical analyses would be performed and what would be done with the data (or the absence of data) of children who did not follow the study to the end.…”

Section: Publishingmentioning

confidence: 99%

Randomness and the Games of Science

Goeman

2016

The Frontiers Collection

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Recently it has become clear that too many findings reported in the scientific literature are irreproducible. We study the causes of this phenomenon from a statistical perspective. Although a certain amount of irreproducible research is unavoidable due to the randomness inherent to scientific observation, two related phenomena conspire to increase the proportion of such findings: publication bias, i.e. the custom that negative findings are usually not published, and confirmation bias, i.e. the human inclination to interpret observations in a way that confirms prior beliefs. Both biases are poorly held in check in the current scientific publication model in which there is no explicit role for the views of a critic, i.e. a scientist with opposing theoretical views. We argue that if researchers are able to play the critic's role imaginatively, they will publish science of higher methodological quality that is not only more reproducible, but also more relevant for theory. To allow for this, we must promote a different view on statistical methodology, seeing statistics not as the gatekeeper of scientific evidence, but as a language scientists may use to discuss uncertainty when they talk about the implications of observations for theory.

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Interventions to prevent obesity in children aged 5 to 11 years old

Spiga,

Davies,

Tomlinson

et al. 2024

Cochrane Database of Systematic Reviews

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Background Prevention of obesity in children is an international public health priority given the prevalence of the condition (and its significant impact on health, development and well‐being). Interventions that aim to prevent obesity involve behavioural change strategies that promote healthy eating or 'activity' levels (physical activity, sedentary behaviour and/or sleep) or both, and work by reducing energy intake and/or increasing energy expenditure, respectively. There is uncertainty over which approaches are more effective and numerous new studies have been published over the last five years, since the previous version of this Cochrane review. Objectives To assess the effects of interventions that aim to prevent obesity in children by modifying dietary intake or ‘activity’ levels, or a combination of both, on changes in BMI, zBMI score and serious adverse events. Search methods We used standard, extensive Cochrane search methods. The latest search date was February 2023. Selection criteria Randomised controlled trials in children (mean age 5 years and above but less than 12 years), comparing diet or 'activity' interventions (or both) to prevent obesity with no intervention, usual care, or with another eligible intervention, in any setting. Studies had to measure outcomes at a minimum of 12 weeks post baseline. We excluded interventions designed primarily to improve sporting performance. Data collection and analysis We used standard Cochrane methods. Our outcomes were body mass index (BMI), zBMI score and serious adverse events, assessed at short‐ (12 weeks to < 9 months from baseline), medium‐ (9 months to < 15 months) and long‐term (≥ 15 months) follow‐up. We used GRADE to assess the certainty of the evidence for each outcome. Main results This review includes 172 studies (189,707 participants); 149 studies (160,267 participants) were included in meta‐analyses. One hundred forty‐six studies were based in high‐income countries. The main setting for intervention delivery was schools (111 studies), followed by the community (15 studies), the home (eight studies) and a clinical setting (seven studies); one intervention was conducted by telehealth and 31 studies were conducted in more than one setting. Eighty‐six interventions were implemented for less than nine months; the shortest was conducted over one visit and the longest over four years. Non‐industry funding was declared by 132 studies; 24 studies were funded in part or wholly by industry. Dietary interventions versus control Dietary interventions, compared with control, may have little to no effect on BMI at short‐term follow‐up (mean difference (MD) 0, 95% confidence interval (CI) ‐0.10 to 0.10; 5 studies, 2107 participants; low‐certainty evidence) and at medium‐term follow‐up (MD ‐0.01, 95% CI ‐0.15 to 0.12; 9 studies, 6815 participants; low‐cer...

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Effect of sugar-sweetened beverages on body weight in children: design and baseline characteristics of the Double-blind, Randomized INtervention study in Kids

Cited by 34 publications

References 50 publications

A Trial of Sugar-free or Sugar-Sweetened Beverages and Body Weight in Children

A Trial of Sugar-free or Sugar-Sweetened Beverages and Body Weight in Children

Randomness and the Games of Science

Interventions to prevent obesity in children aged 5 to 11 years old

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