Effect of Strength Training on Lipid and Inflammatory Outcomes: Systematic Review With Meta-Analysis and Meta-Regression

Costa, R. D. D.; Buttelli, Adriana Cristine Koch; Vieira, Alexandra; Coconcelli, Leandro; Magalhães, Rafael de Lima; Delevatti, Rodrigo Sudatti; Kruel, Luiz Fernando Martins

doi:10.1123/jpah.2018-0317

Cited by 41 publications

(45 citation statements)

References 85 publications

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“…It is suggested that the effect of physical activity on PON activity is associated with the PON1-192 gene polymorphism 66 . Moreover, different age of the study population may also partly explain the differences between previous findings as this enzyme’s activity is very low at birth and increases with age 20 . The decrease in PON activity observed in our study’s endurance group may indicate increased lipid oxidation, which may be associated with a higher risk of cardiovascular disease.…”

Section: Discussionmentioning

confidence: 72%

“…Several meta-analyses have shown a significant effect of both endurance and strength training on anthropometric and cardiometabolic parameters, providing evidence for reductions in body weight, body mass index (BMI), waist circumference, fat mass (FM), improved lipid profile, decreased glucose, insulin levels and blood pressure (BP) 16 – 20 . Although the benefits of endurance and strength training alone are well documented, studies comparing the effect of endurance and endurance-strength training on body composition and cardiometabolic markers have proved inconsistent.…”

Section: Introductionmentioning

confidence: 99%

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The effect of endurance and endurance-strength training on body composition and cardiometabolic markers in abdominally obese women: a randomised trial

Jamka

Mądry

Krzyżanowska-Jankowska

et al. 2021

Sci Rep

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Studies comparing the effect of endurance and endurance-strength training on cardiometabolic markers provided inconsistent results. Therefore, the study aimed to compare the effect of endurance and endurance-strength training on body composition and cardiometabolic parameters in abdominally obese women. In this randomised trial, 101 subjects were included and divided into endurance (n = 52) and endurance-strength (n = 49) training. During the 12-week intervention, participants performed supervised one-hour training three times a week. Body composition, blood pressure (BP), markers of glucose and lipid homeostasis, and myoglobin levels were measured before and after the intervention. In total, 85 subjects completed the trial. Both interventions decreased fat mass and visceral adipose tissue and increased free fat mass, appendicular lean mass index and lean mass index. Neither endurance training nor endurance-strength training affected glucose and lipid metabolism. However, only endurance training significantly decreased paraoxonase and myoglobin levels. Both training programmes significantly decreased BP, with a more reduction of diastolic BP noted in the endurance group. In conclusion, both training programmes had a favourable effect on body composition but did not improve glucose and lipid homeostasis. Besides, endurance training decreased paraoxonase activity and myoglobin levels and was more effective in reducing BP.The study was registered with the German Clinical Trials Register (DRKS) within the number: DRKS00019832 (retrospective registration), date of registration: 26/02/2020.

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Section: Discussionmentioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

The effect of endurance and endurance-strength training on body composition and cardiometabolic markers in abdominally obese women: a randomised trial

Jamka

Mądry

Krzyżanowska-Jankowska

et al. 2021

Sci Rep

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“…Regarding the RT program, no effects were observed on any of the cardiovascular risk parameters when comparing trained groups to untrained groups, although circulating levels of Total chol, LDL-chol and HDL-chol were decreased in the P+RT group, and both trained groups revealed a decrease in TG. Despite the recent meta-analyses describing beneficial effects of RT on circulating lipid levels in adults [ 15 , 85 ], multiple trials investigating RT effects on blood lipid levels observed no effects in postmenopausal women and older adults [ 19 , 21 , 68 , 86 ]. Thus, several studies have assessed this question by examining the individual response to RT in older adults.…”

Section: Discussionmentioning

confidence: 99%

Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women

et al. 2021

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Resistance training (RT) and n-3 polyunsaturated fatty acids (n-3 PUFA) supplementation have emerged as strategies to improve muscle function in older adults. Overweight/obese postmenopausal women (55–70 years) were randomly allocated to one of four experimental groups, receiving placebo (olive oil) or docosahexaenoic acid (DHA)-rich n-3 PUFA supplementation alone or in combination with a supervised RT-program for 16 weeks. At baseline and at end of the trial, body composition, anthropometrical measures, blood pressure and serum glucose and lipid biomarkers were analyzed. Oral glucose tolerance tests (OGTT) and strength tests were also performed. All groups exhibit a similar moderate reduction in body weight and fat mass, but the RT-groups maintained bone mineral content, increased upper limbs lean mass, decreased lower limbs fat mass, and increased muscle strength and quality compared to untrained-groups. The RT-program also improved glucose tolerance (lowering the OGTT incremental area under the curve). The DHA-rich supplementation lowered diastolic blood pressure and circulating triglycerides and increased muscle quality in lower limbs. In conclusion, 16-week RT-program improved segmented body composition, bone mineral content, and glucose tolerance, while the DHA-rich supplement had beneficial effects on cardiovascular health markers in overweight/obese postmenopausal women. No synergistic effects were observed for DHA supplementation and RT-program combination.

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“…Muscle strength can be improved by muscle-strengthening activities, and resistance training, a typical muscle-strengthening activity, promotes decreases in TC, TG, and LDL-C levels and increases in HDL-C level. 32 In addition, skeletal muscle is a main tissue of fatty acid uptake and oxidation. 33 Taken together, grip strength may be a risk marker of the incidence of dyslipidemia and its components.…”

Section: Discussionmentioning

confidence: 99%

Physical Fitness and Dyslipidemia Among Japanese: A Cohort Study From the Niigata Wellness Study

Momma

Kato

Sawada

et al. 2021

Journal of Epidemiology

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Background Grip strength reflects systemic muscle strength and mass and is reportedly associated with various metabolic variables. However, its prognostic association with dyslipidemia is unknown. We examined the association of grip strength and other physical fitness markers with the incidence of dyslipidemia among Japanese adults. Methods A total of 16,149 Japanese (6,208 women) individuals aged 20–92 years who underwent a physical fitness test between April 2001 and March 2002 were included in this cohort study. Grip strength, vertical jump, single-leg balance with eyes closed, forward bending, and whole-body reaction time were evaluated at baseline. Dyslipidemia was annually determined based on fasting serum lipid profiles and self-reported dyslipidemia from April 2001 to March 2008. Results During the follow-up period, 4,458 (44.9%) men and 2,461 (39.6%) women developed dyslipidemia. A higher relative grip strength (grip strength/body mass index) was associated with a lower incidence of dyslipidemia among both men and women ( P for trend <0.001). Compared with those for the first septile, the hazards ratios and 95% confidence intervals (CIs) for the seventh septile were 0.56 (95% CI, 0.50–0.63) for men and 0.69 (95% CI, 0.58–0.81) for women. Moreover, relative vertical jump (vertical jump strength/body mass index) was also inversely associated with the incidence of dyslipidemia among both men and women ( P for trend <0.001). There was no association between other physical fitness and dyslipidemia among both men and women. Conclusion Relative grip strength and vertical jump may be useful risk markers of the incidence of dyslipidemia.

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Effect of Strength Training on Lipid and Inflammatory Outcomes: Systematic Review With Meta-Analysis and Meta-Regression

Cited by 41 publications

References 85 publications

The effect of endurance and endurance-strength training on body composition and cardiometabolic markers in abdominally obese women: a randomised trial

The effect of endurance and endurance-strength training on body composition and cardiometabolic markers in abdominally obese women: a randomised trial

Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women

Physical Fitness and Dyslipidemia Among Japanese: A Cohort Study From the Niigata Wellness Study

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