Effect of storage on the chemical composition and biological activity of several popular South African medicinal plants

Stafford, G.I.; Jäger, Anna K.; Staden, J. Van

doi:10.1016/j.jep.2004.10.021

Cited by 90 publications

(73 citation statements)

References 20 publications

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“…Poor antibacterial activity against both Grampositive and Gram-negative bacteria was, however, shown with M. natalensis extracts [103]. e storage of the bulb did not have any negative in�uence on the antibacterial activity of the extracts but actually increased the activity [112]. Sparg et al [103] con�rmed that there are no alkaloids present in M. natalensis.…”

Section: Phytochemistry and Biological Activitymentioning

confidence: 98%

Commercially Important Medicinal Plants of South Africa: A Review

Street

Prinsloo

2012

Journal of Chemistry

141

114

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ere is a growing interest in natural plant-based remedies as a source for commercial products. Around 80% of the South African population use traditional medicines to meet their primary health care needs; however, only a few South African medicinal plants have been exploited to their full potential in terms of commercialization. e opportunity for bioprospecting of plant compounds for novel pharmaceuticals remains largely untapped. Certain renowned medicinal plants of international acclaim including buchu and rooibos are currently contributing to local enterprise; however, other exciting opportunities exist for commonly used plants which have not yet reached the international arena. is paper focuses on the key research and development contributions of 10 commercially important medicinal plants of South Africa. �raditional uses, scienti�c validation, commercialisation developments, as well as both potential opportunities and setbacks are discussed.

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Section: Phytochemistry and Biological Activitymentioning

confidence: 98%

Commercially Important Medicinal Plants of South Africa: A Review

Street

Prinsloo

2012

Journal of Chemistry

141

114

View full text Add to dashboard Cite

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“…In some cases, the reported data were carried out for different plant parts/extracts only by diffusion methods or described no significant MIC values (Al-Fatimi et al, 2007;Stafford et al, 2005;Kambizi & Afolayan, 2001;Kumar et al, 1997). However, significant antibacterial activity was previously described for T. emetica (Shai et al, 2008;Germanò et al, 2005), Cassia occidentalis L. (Fabaceae) (Yadav et al, 2010) and Tabernaemontana elegans Stapf.…”

Section: Chenopodium Ambrosioides L (Amaranthaceae) Kanunka Unconomentioning

confidence: 98%

Antibacterial activity of some African medicinal plants used traditionally against infectious diseases

Madureira

Ramalhete

Mulhovo

et al. 2011

Pharmaceutical Biology

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“…Extracts of various species have been used to treat topical infections, respiratory ailments and as dressing of circumcision wounds (Stafford et al, 2005). The antimicrobial activities of extracts from Helichrysum species have been widely reported (Bougatsos et al, 2004;Eloff, *Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

In vitro time kill assessment of crude methanol extract of Helichrysum pedunculatum leaves

Aiyegoro¹,

O²,

Afolayan³

et al. 2008

Afr. J. Biotechnol.

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The in vitro antibacterial activities and time kill regimes of crude methanol extract of Helichrysum pedunculatum was assessed using standard microbiological procedures. The experiment was conducted against a panel of bacterial species made up of clinical, environmental and reference strains. The extract was active against eleven of the twenty-one bacteria tested at a concentration of 10 mg/ml. Minimum Inhibitory Concentration (MIC) values for all the susceptible bacteria ranged between 0.1 -5.0 mg/ml. The average log reduction in viable cell count in time kill assay ranged between 0.17 Log 10 to 6.37 Log 10 cfu/ml after 6 h of interaction, and between 0.14 Log 10 and 6.99 Log 10 cfu/ml after 12 h interaction in 1×MIC and 2×MIC of the extract. The extract was bactericidal against 8 of the test bacteria at 1×MIC and against 9 of the test bacteria at 2×MIC from 12 h interaction period. At both MIC levels, the extract was bactericidal to all the reference strains and four of the six environmental strains at both MIC levels after 12 h of interaction. Also the extract was bactericidal to four of the six environmental strains at both MIC levels after 12 h of interaction and bacteriostatic during the first 6 h of interaction. Inhibitory levels of crude methanol extract of H. pedunculatum could be bacteriostatic or bactericidal independent of Gram's characteristic.

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Effect of storage on the chemical composition and biological activity of several popular South African medicinal plants

Cited by 90 publications

References 20 publications

Commercially Important Medicinal Plants of South Africa: A Review

Commercially Important Medicinal Plants of South Africa: A Review

Antibacterial activity of some African medicinal plants used traditionally against infectious diseases

In vitro time kill assessment of crude methanol extract of Helichrysum pedunculatum leaves

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