Effect of St. John’s wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial

Kaplan, Volkan; Erbaşar, Güzin Neda Hasanoğlu; Ciğerim, Levent; Turgut, Hilal Altay; Cerit, Abdullah

doi:10.1007/s00784-020-03639-0

Cited by 13 publications

(22 citation statements)

References 35 publications

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“…Organic oils, including olive oil, have been known for their antioxidant, anti-antioxidant, anti-inflammatory, and antimicrobial properties [21] and have been used in dermatological products for some time [22]. However, proper testing in formulation for oral products has only recently been tested and demonstrated both for caries [23] and surgical and periodontal applications [24].…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility and Effectiveness of a Novel, Organic Olive Oil-Based Denture Adhesive: A Multicenter Randomized and Placebo-Controlled Clinical Trial

Azevedo

Correia

Almeida

et al. 2021

IJERPH

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To assess the clinical efficacy of a novel, organic olive oil-based denture adhesive and its effect on Candida albicans growth in maxillary edentulous individuals wearing complete dentures, individuals were selected from two dental schools in Portugal and Spain. Twenty-eight complete dentures were relined, following a standardized protocol. The novel product (test) was compared with a commercialized adhesive (control) and Vaseline (placebo) randomly assigned in a cross-study design. The retention resistance was measured with a gnathometer and a dynamometer. The patients related outcome evaluations with a five-point questionnaire, and the Candida albicans growth in a Sabouraud dextrose agar (SDA) medium was used to evaluate differences between the placebo and experimental product. Twenty-three participants were included. The dynamometer evaluation showed significant differences between not using a denture adhesive and using either (experimental, p = 0.03; control, p = 0.04) and no significant differences between the two adhesives (p > 0.05). In the subjective analysis, the experimental adhesive showed a significantly longer effectiveness (p = 0.001), and the control reported better results in taste (p = 0.03) and in chewing (p = 0.001). The test adhesive showed better (p < 0.001) Candida albicans growth inhibition. The experimental adhesive showed longer effectiveness than the control and the placebo with a better inhibition capacity for the growth of Candida albicans. Patients reported better abilities for speech, chewing, taste, and retirement in the control adhesive.

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Section: Introductionmentioning

confidence: 99%

Biocompatibility and Effectiveness of a Novel, Organic Olive Oil-Based Denture Adhesive: A Multicenter Randomized and Placebo-Controlled Clinical Trial

Azevedo

Correia

Almeida

et al. 2021

IJERPH

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“…Table 1 summarized the characteristics of the included trial studies. From the 25 trials involving 1184 participants, the majority were conducted in India (n = 19), 11,13,14,18,20,[39][40][41][42][43][44][45][46][47][48][49][50][51] whereas the remaining trials were implemented in Turkey, 43 Egypt, 52 Germany, 21 Malaysia, 53 and two with no reported region of study. 54,55 The number of participants included in each trial was comparatively small, ranging between 8 to 75.…”

Section: Participantmentioning

confidence: 99%

“…11,14,18,20,[39][40][41][44][45][46][50][51][52][53][54]56,57 Of the remaining eight trials, six trials recruited participants with mild to moderate gingivitis, 13,42,[47][48][49]55 one trial included participants with Xerostomia, 21 and one trial included post-dental operative adults. 43 Trials comprised of mainly adults. 20,[42][43][44][47][48][49][50]53,[55][56][57] Five trials included children 14,41,45,46,52 and adolescents, 11,18,39,51,54 respectively.…”

Section: Participantmentioning

confidence: 99%

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The effect of oil pulling in comparison with chlorhexidine and other mouthwash interventions in promoting oral health: A systematic review and meta‐analysis

Jong,

Ooi,

Teoh

2023

Int J Dental Hygiene

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ObjectivesA meta‐analytic review was performed to critically synthesize the evidence of oil pulling on improving the parameters of gingival health, plaque control and bacteria counts against chlorhexidine and other mouthwash or oral hygiene practices.MethodsDatabases including Medline, Embase and bibliographies were searched from inception to 1 April 2023. Randomized controlled trials (RCTs) with 7 days or longer duration of oil pulling with edible oils in comparison to chlorhexidine or other mouthwashes or oral hygiene practice concerning the parameters of plaque index scores (PI), gingival index scores (GI), modified gingival index scores (MGI) and bacteria counts were included. Cochrane's Risk of Bias (ROB) tool and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework were employed to determine the quality of evidence. Two authors independently conducted study selection and data extraction. Meta‐analyses of the effect of oil pulling on the parameters were conducted using an inverse‐variance random‐effects model.ResultsTwenty‐five trials involving 1184 participants were included. Twenty‐one trials comparing oil pulling (n = 535) to chlorhexidine (n = 286) and non‐chlorhexidine intervention (n = 205) were pooled for meta‐analysis. More than half of the trials (n = 17) involved participants with no reported oral health issues. The duration of intervention ranged from 7 to 45 days, with half of the trials using sesame oil. When compared to non‐chlorhexidine mouthwash interventions, oil pulling clinically and significantly improved MGI scores (Standardized mean difference, SMD = −1.14; 95% confidence interval [CI]: −1.31, −0.97). Chlorhexidine was more effective in reducing the PI scores compared to oil pulling, with an SMD of 0.33 (95% CI: 0.17, 0.49). The overall quality of the body of evidence was very low.ConclusionsThere was a probable benefit of oil pulling in improving gingival health. Chlorhexidine remained superior in reducing the amount of plaque, compared to oil pulling. However, there was very low certainty in the evidence albeit the clinically beneficial effect of oil pulling intervention.

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“…Hyperforin, a naphthodianthrone, acts by halting COX-1 and lipo-oxygenase. Multiple studies have shown the anti-phlogistic properties of hypericum oil with accelerated wound healing [ 20 , 21 ].…”

Section: Reviewmentioning

confidence: 99%

Insight of Ethnomedicines in Dentistry: A Brief Review

Gupta¹,

Jadhav²,

Bhola³

et al. 2022

Cureus

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Ethnomedicines in the literature compare the therapeutic efficacy of various herbs based on active ingredients of plants and animals. The application of phytomedicines in the field of dentistry is uncommon. The main objective of this article is to access the efficacy of ethnomedicines and newly evolving treatment modalities in reducing post-op complications following dentoalveolar surgeries. Inclusion criteria were selected according to the population, intervention, control, and outcomes (PICO) format. Case reports, case series, retrospective studies, and studies with inappropriate reporting of outcomes were all excluded. An electronic search of English literature in PubMed was performed using the keywords Ethnomedicine, Antiinflammatory, Analgesics, Therapeutic herbs, Herbal mouthwashes, Third molar surgery. A total of 25 articles were selected, of which three were on herbal mouthwashes and 22 were on anti-inflammatory effect. All the articles were regarding the therapeutic effect of the herbs. The present paper studies various traditionally used therapeutic herbs, their benefits, and shortcomings with their application in dentistry. This study has shown the different herbal alternatives to conventionally used drugs in relation to third molar.

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Effect of St. John’s wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial

Cited by 13 publications

References 35 publications

Biocompatibility and Effectiveness of a Novel, Organic Olive Oil-Based Denture Adhesive: A Multicenter Randomized and Placebo-Controlled Clinical Trial

Biocompatibility and Effectiveness of a Novel, Organic Olive Oil-Based Denture Adhesive: A Multicenter Randomized and Placebo-Controlled Clinical Trial

The effect of oil pulling in comparison with chlorhexidine and other mouthwash interventions in promoting oral health: A systematic review and meta‐analysis

Insight of Ethnomedicines in Dentistry: A Brief Review

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