Effect of South Sulawesi Propolis in Sevoflurane Anesthesia-Induced Rat Model During Weaning Period: Study Levels of IL-6, TNF⍺, IL-10, and PSD-95 of the Prefrontal Cortex
Nuh Gusta Ady Yolanda,
Trinovita Andraini,
Roman Ardian Goenarjo
et al.
Abstract:Background: A recent study discovered that exposure to the anesthetic gas sevoflurane in the early years of life can impact cognitive function. Objectives: This study aims to investigate the effects of prolonged and repeated exposure to sevoflurane during the weaning period and whether the administration of propolis, a well-known herbal substance with anti-inflammatory properties, has a beneficial effect on inflammation and synaptic markers in the prefrontal cortex area, as well as its effect on spatial workin… Show more
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