Effect of Soft Cheese in Reducing of Lipid Profile and Liver Enzymes for Rats with Fat Disorder

Abstract

Aim: This study was designed to determine the impact of soft cheese upon total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), very low-density lipoprotein cholesterol (VLDL) and the efficacy of liver enzymes AST, ALT, and ALP in hyperlipidemia experimental Sprague-Dawley rats. Materials & Methodology: Rats were divided into five groups (six rats each), healthy control group, hyperlipidemia control group, and three hyperlipidemia groups were fed on regular soft cheese (T1), cheese supplementation with probiotics (T2), and cheese supported with Nigella sativa L (T3). Following 28 days, Result: the results revealed a significant decrease (p<0.05) in total cholesterol in groups of rats that were feeding on chees T1, T2 and T3 (179.83, 138.71 and 135.06 mg/ dl, respectively) compared to hyperlipidemia control group (250.98 mg/dl), T1, T2 and T3 groups showed a significant decrease in LDL levels (153.45, 104.39, 97.47 mg/dl respectively) compared to hyperlipidemia control groups (246 mg/dl). However, an increase of HDL levels were noticed in the same groups in contrast, T3 group revealed significantly decreased in the liver enzymes (28.45, 67.29, 98.16 IU/L) of ALT, AST and ALP respectively compared to hyperlipidemia control group (41.27, 88.35, 108.72)IU/L respectively.

Effectiveness of Soft Cheese Fortified by Zinc Oxide Nanoparticles and Artemisia Herba Alba Extract on Blood Lipid Profile of Hypercholesterolemic Rats

“…It also agreed with the study [23] which found that oral administration of zinc nanoparticles had a positive effect on lipid-painter improvement. It also agreed with the study of [24] which demonstrated the possibility of soft cheese in lowering the fat levels of feeding rats on high fat leeches and its ability to process them. There has also been a positive change in fat levels in the nutritious rat aggregates with high calorie tenderness with nanoscale zinc oxide dosage and thus a decrease in their levels which has been positively reflected in animal health.…”

“…As between [33] nutrition with a high calorie stick caused a rise in liver-saturated fatty acids and therefore elevated liver enzymes as a result of liver damage. These findings also coincided with the findings of [34]. In their study, the nutrition of soft cheese gave a positive role in the level of liver enzymes compared to overlipid rats and was not treated.…”