Effect of sodium hypochlorite on bonding performance of universal adhesives to pulp chamber dentin

Effect of various irrigation protocols and antioxidant application on bonding performance of two adhesive systems to coronal dentin

“…This might be due to demineralization of dentin by 17% EDTA application, that is a debilitated acid etching representative along with consequent dentin deproteinization executed by NaOCl. It was reported that NaOCl decomposes resulting in free oxygen production preventing the resin polymerization and thus the bond strength is significantly compromised ( 3 ). This was in accordance with Garcia et al .…”

“…Furthermore, effective coronal seal promotes the success of RCTs which can be accomplished by proper bonded restorations. So as to, the functional stresses can be conveyed throughout the bonded interface to reinforce the weakened tooth structure ( 3 ). Additionally, different deproteinizing irrigants were reported to dissolve the organic component of the smear layer on the prepared dentin surfaces upon bonding using SE adhesives that can modify the smear layer integrating it into the hybrid layer, revealing acceptable bonding performance ( 31 ).…”

“…Additionally, different deproteinizing irrigants were reported to dissolve the organic component of the smear layer on the prepared dentin surfaces upon bonding using SE adhesives that can modify the smear layer integrating it into the hybrid layer, revealing acceptable bonding performance ( 31 ). This was found to decrease the organic to inorganic contents ratio on the coronal dentin surface, leading to thin smear layer formation which might enhance the adhesive monomer infiltration owed to elimination of smear layer organic contents ( 3 ). In the same context, Tay et al .…”

“…Some factors could enhance tissue dissolving by NaOCl, such as pH rising, ultrasound agitation, increased working time, and the temperature solution and its concentration ( 1 ). NaOCl has low molecular weight enabling its diffusion inside hydroxyapatite-encapsulated collagen matrix, thus denaturing the collagen, oxidizing its organic matrix, while negatively altering dentin mechanical properties ( 3 ). Consequently, using a combination of inorganic and organic tissue-dissolving irrigating solutions was suggested ( 2 ).…”

In vitro cytotoxicity and antibacterial activity of hypochlorous acid antimicrobial agent

“… 11 During endodontics, NaOCl irrigants are often used to better remove and inactivate the smear layer containing residual bacteria after root canal preparation. 10 , 12 Accordingly, the American Association of Endodontics (AAE) Clinical Considerations for Regenerative Surgery mentions the use of 1.5% NaOCl as an irrigant. 13 However, when NaOCl degrades collagen type I, the organic component of dentin, it negatively affects the mechanical behavior of dentin tissue and its restoration.…”