Effect of sodium copper chlorophyllin on lipid peroxidation. IX On the antioxidative components in commercial preparations of sodium copper chlorophyllin.

HPLC–MS analysis of the green food colorant sodium copper chlorophyllin

“…Cu chlorin e 6 and Cu isochlorin e 4 were reported to be among the constituents of sodium copper chlorophyllin (Sato, Fujimoto, Sakai, Aimoto, Kimura, & Murata, 1986). Other studies found the same main components of sodium copper chlorophyllin: Cu chlorin e 4 , Cu chlorin e 6 , Cu rhodin g 7 , and Cu pheophorbide a (Inoue et al, 1994;Ferruzzi et al, 2002).…”

Antioxidant activity of chlorophylls and their derivatives

“…The highest activities were found for Cu-substituted chlorins. Previously, Sato et al (1986) identified Cuchlorin e4 as the major antioxidant found in commercial grade sodium Cu-chlorophyllin, by measuring its antioxidant activity in rat liver homogenates.…”

Copper chlorophyllin: A food colorant with bioactive properties?

“…Sato et al (1986) also investigated the antioxidant activity of this pigment against Fe 2 + and ascorbateinduced lipid peroxidation in rat liver homogenate. They observed that two of the Cu-Chl fractions isolated by thin layer chromatography (TLC) completely inhibited thiobarbituric acid reactive substances (TBARS) formation.…”

“…Although various studies have demonstrated the antioxidant potential of Cu-Chl under different oxidative stress conditions, many of them have solely attributed its activity to the presence of a specific copper chlorin (Fahey et al, 2005;Sato et al, 1986). Therefore, authors are concerned about the use of impure commercial Cu-Chl and suggest the use of copper chlorin compounds, as pure as possible.…”