Effect of Sodium Bicarbonate and Beta-Alanine on Repeated Sprints During Intermittent Exercise Performed in Hypoxia

Saunders, Bryan; Sale, Craig; Harris, Roger C.; Sunderland, Caroline

doi:10.1123/ijsnem.2013-0102

Cited by 44 publications

(48 citation statements)

References 41 publications

(39 reference statements)

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“…In addition, although Fig 3 demonstrates a slight trend in the β-alanine group to improve total time and the Δ% improved ~3% for time variables in the β-alanine group, whereas in the placebo group the improvement was only ~0.5% (Table 1), these differences (between-subject factor and within-subject factor) were very small and widely dispersed, making them non-significant. Thus, the findings in RSA 2 shown in the present study were in accordance with Saunders et al [19], who investigated the effects of β-alanine supplementation on RSA evaluated after efforts that simulated the physical demands of a football match and also did not find improvements by conventional statistical analysis.…”

Section: Discussionsupporting

confidence: 92%

“…On the other hand, the present study was the first to report positive outcomes, through magnitude-based inference analysis, of β-alanine supplementation on RSA. Ducker et al [18] and Saunders et al [19] despite using this statistical approach, which is ideal for detecting small changes in sports performance, did not find meaningful effects of β-alanine supplementation on RSA.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

et al. 2016

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The purpose of this study was to investigate the effect of four weeks of β-alanine supplementation on repeated sprint ability in water polo players. Twenty-two male water polo players participated in the study, divided randomly into two homogeneous groups (placebo and β-alanine groups). The study design was double-blind, parallel and placebo controlled. Before and after the supplementation period (28 days), the athletes performed two specific repeated sprint ability tests interspaced by a 30-minute swimming test. Participants received 4.8g∙day-1 of the supplement (dextrose or β-alanine) on the first 10 days and 6.4g∙day-1 on the final 18 days. There was no significant group-time interaction for any variable. The qualitative inference for substantial changes demonstrated a likely beneficial effect in the β-alanine group (β-alanine vs placebo) for mean time (6.6±0.4s vs 6.7±0.4s; 81% likely beneficial), worst time (6.9±0.5s vs 7.1±0.5s; 78% likely beneficial) and total time (39.3±2.5s vs 40.4±2.5s; 81% likely beneficial) in the first repeated sprint ability set and for worst time (7.2±0.6s vs 7.5±0.6s; 57% possible beneficial) in the second repeated sprint ability set. Further, was found substantial change for total time for both repeated sprint ability tests (80.8±5.7s vs 83.4±5.6s; 52% possible beneficial). To conclude, four weeks of β-alanine supplementation had a likely beneficial effect in the first set of repeated sprint ability tests and a possible beneficial effect for worst time in the second set performed in a specific protocol in water polo players.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

et al. 2016

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“…The current investigation is the first to demonstrate a significant and meaningful improvement in performance from NaHCO 3 under acute hypoxic conditions, in contrast with as previous investigations reporting no effect (Saunders et al 2014b; Flinn et al 2014). The conflicting results to previous investigations may be attributed to the intensity and type of exercise, which were supra-maximal and intermittent in both previous studies, or the training status of participants, who were recreationally trained.…”

Section: Discussioncontrasting

confidence: 89%

Determinants of curvature constant (W’) of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis

et al. 2017

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PurposeThis study investigated the effect of induced alkalosis on the curvature constant (W’) of the power-duration relationship under normoxic and hypoxic conditions.MethodsEleven trained cyclists (mean ± SD) Age: 32 ± 7.2 years; body mass (bm): 77.0 ± 9.2 kg; VO2peak: 59.2 ± 6.8 ml·kg−1·min−1 completed seven laboratory visits which involved the determination of individual time to peak alkalosis following sodium bicarbonate (NaHCO3) ingestion, an environment specific ramp test (e.g. normoxia and hypoxia) and four x 3 min critical power (CP) tests under different experimental conditions. Participants completed four trials: alkalosis normoxia (ALN); placebo normoxia (PLN); alkalosis hypoxia (ALH); and placebo hypoxia (PLH). Pre-exercise administration of 0.3 g.kg−1 BM of NaHCO3 was used to induce alkalosis. Environmental conditions were set at either normobaric hypoxia (FiO2: 14.5%) or normoxia (FiO2: 20.93%).ResultsAn increase in W’ was observed with pre-exercise alkalosis under both normoxic (PLN: 15.1 ± 6.2 kJ vs. ALN: 17.4 ± 5.1 kJ; P = 0.006) and hypoxic conditions (ALN: 15.2 ± 4.9 kJ vs. ALN: 17.9 ± 5.2 kJ; P < 0.001). Pre-exercise alkalosis resulted in a larger reduction in bicarbonate ion (HCO3 −) concentrations during exercise in both environmental conditions (p < 0.001) and a greater blood lactate accumulation under hypoxia (P = 0.012).ConclusionPre-exercise alkalosis substantially increased W’ and, therefore, may determine tolerance to exercise above CP under normoxic and hypoxic conditions. This may be due to NaHCO3 increasing HCO3 − buffering capacity to delay exercise-induced acidosis, which may, therefore, enhance anaerobic energy contribution.

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“…However, with only six participants per condition, these results cannot directly be generalized. Moreover, two recent studies reported no ergogenic effect of co-supplementation on repeated sprints (5 Â 6 s) performed in hypoxia [35] and maximal sprint swimming [23], but participants were not blinded in the latter study. In general, the majority of the studies did find a small but nonsignificant additive effect of co-supplementation of beta-alanine and NaHCO 3 , which may be meaningful in performance terms to elite athletes in a real-world setting.…”

Section: Does Combined Beta-alanine and Nahco 3 Supplementation Have mentioning

confidence: 98%

Beta-alanine supplementation, muscle carnosine and exercise performance

Blancquaert

Everaert

Derave

2015

Current Opinion in Clinical Nutrition and Metabolic Care

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On the basis of the millimolar presence of carnosine in mammalian muscles, it must play a critical role in skeletal muscle physiology. The recent number of studies shows that this is related to an improved exercise homeostasis and excitation-contraction coupling. Recent developments have led to the optimization of the beta-alanine supplementation strategies to elevate muscle carnosine content, which are helpful in its application in sports and to potential future therapeutic applications.

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Effect of Sodium Bicarbonate and Beta-Alanine on Repeated Sprints During Intermittent Exercise Performed in Hypoxia

Cited by 44 publications

References 41 publications

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

Determinants of curvature constant (W’) of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis

Beta-alanine supplementation, muscle carnosine and exercise performance

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