Effect of Smoking on Platelet Count and Platelet Parameters: An Observation

Abstract

Arterial thrombosis occurs with increased frequency in cigarette smokers. It is believed that disturbance of platelet function, especially aggregation, is the essential mechanism responsible for this pathology. However, the effect of smoking on the quantity of platelets might be another contributing factor. The effect of smoking on platelet count is still controversial. We performed a cross section-al study to compare the platelet count and platelet parameters in Thai police who are smokers and non-smokers. A total of 30 Thai police in Bangkok were included in this study. Of the 30 police, there are 5 non-smokers and 25 smokers. The platelet counts and platelet parameters of the subjects were not significantly different between smokers and non-smokers.

Short‐Term E‐Cigarette Exposure Increases the Risk of Thrombogenesis and Enhances Platelet Function in Mice

“…Furthermore, while the effect of “smoke” on platelet count remains controversial, with studies showing it to be increased51 or unaffected,52, 53 we sought to examine whether e‐cigarettes would produce any effects under our experimental conditions. Our data revealed no difference in platelet count between clean air– and e‐cigarette–exposed mice, that is, 526±64 versus 571±96 (thousand/µL; P =0.323), respectively, at least under the present experimental conditions.…”

“…This is consistent with our hemostasis findings, as a (significant) decrease in platelet count would be expected to result in a bleeding diathesis, and not the shortened bleeding time we observed. As for the effects of traditional tobacco, studies are controversial, with some showing the platelet counts to be increased51 or unaffected 52, 53. These differences could be attributed, in part, to the different exposure conditions and study populations/subjects.…”

Causes of Variation in The Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios: a Twin-Family Study

“…PLR, however, was not related to smoking [23] in the general population, and neither was platelet count in this study. Lack of evidence for an association between platelet count and smoking has been reported more often [25,26], though lower platelet levels in smokers have also been observed [27,28].…”

Evaluation of Haemorheological Parameters in Cigarette Smokers in Western Nigeria

“…Brumit and Baker found no correlation between platelet count and smoking in healthy volunteers (Brumit and Baker, 2000). Also Dotevall et al noted no changes in platelet count in female smokers and non-smokers (Dotevall et al, 1992), and Suwansaksri et al observed no alteration in platelet in smokers and non-smokers (Suwansaksri et al, 2004). According to Blann et al, smoking two cigarettes a day by chronic smokers of both sexes does not affect the platelet count (Blann et al, 1998).…”