2003
DOI: 10.1302/0301-620x.85b2.13717
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Effect of smoking on early complications after elective orthopaedic surgery

Abstract: Smoking is an important risk factor for the development of postoperative pulmonary complications after major surgical procedures. We studied 811 consecutive patients who had undergone hip or knee arthroplasty, recording current smoking and drinking habits, any history of chronic disease and such intraoperative factors as the type of anaesthesia and the type and duration of surgery. We recorded any postoperative complications occurring before discharge from hospital. There were 232 smokers (28.6%) and 579 non-s… Show more

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Cited by 277 publications
(187 citation statements)
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References 32 publications
(19 reference statements)
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“…For closed fractures, smoking was the only factor associated with an increased risk of SSI in multivariate analysis. This is consistent with prior studies of plastic surgery of the upper extremity and orthopaedic surgery [2,6,13,20]. Smoking appears to suppress the immune system [18].…”
Section: Discussionsupporting
confidence: 91%
“…For closed fractures, smoking was the only factor associated with an increased risk of SSI in multivariate analysis. This is consistent with prior studies of plastic surgery of the upper extremity and orthopaedic surgery [2,6,13,20]. Smoking appears to suppress the immune system [18].…”
Section: Discussionsupporting
confidence: 91%
“…Both of these risk factors have been reported to increase the risk of short-term complications such as wound infections and pulmonary events following THR (Moller et al 2003, Sadr Azodi et al 2006. Previous studies have not found any significant association between high BMI and the risk of implant dislocation in patients undergoing primary THR (Woolson and Rahimtoola 1999, Khatod et al 2006, McLaughlin and Lee 2006.…”
mentioning
confidence: 99%
“…This finding is consistent with prior evidence that smoking impairs wound healing and predisposes one to infection. 20,21,28 We also found that the occurrence of CSF leak was associated with infratentorial surgery and extended treatment with corticosteroids, and that use of a synthetic dural graft decreased the likelihood of occurrence ( Table 6). These findings are consistent with a large body of experience describing CSF leak rates following infratentorial procedures of 8%-17%.…”
Section: Discussionmentioning
confidence: 70%