Effect of small dose intermittent IV pethidine in combination with diclofenac for post operative pain relief

Banik, Debabrata; Hye, Abdul; Akhtaruzzaman, Akm; Aziz, Lutful; Yeasmeen, Sabina; Iqbal, Khadija

doi:10.3329/jbsa.v22i2.18140

Cited by 3 publications

(1 citation statement)

References 23 publications

(13 reference statements)

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“…6,7 Opioid analgesics for post-op pain relief are gaining numbers, but on the other hand it ends up with dangerous after effects like CNS depression and altered GI motility. 8 Recently physicians have focused on Non-steroidal anti-inflammatory https://doi.org/10.29309/TPMJ/2021.28.09.5885 2 drugs (NSAID) for pain relief because of various anticipated problems associated with opioids. 9,10 Diclofenac is amongst the NSAIDs class of medicine having an effective post-operative pain relief resulting in lowering postoperative narcotic demands.…”

Section: Introductionmentioning

confidence: 99%

To compare efficacy of Diclofenac by intramuscular route and rectal route in post surgical pain.

Zulfiqar¹,

Ashraf²,

Khan³

et al. 2021

TPMJ

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Objective: This study was carried out in Lahore General Hospital, Lahore to test the results of Intramuscular vs Suppository form of Diclofenac Sodium on the severity of post-surgical pain in patients who underwent Cesarean delivery under Subarachnoid Block. Study Design: Randomized Study. Setting: Lahore General Hospital, Lahore. Period: April 2019 to September 2019. Material & Methods: This was a double-blind run on 100 patients who underwent for cesarean delivery irrespective of any indication for the procedure. The pain sufferers had been randomly divided into 2 groups. The group A: who received Diclofenac Sodium in the form of suppository and Group B: who received intramuscular Diclofanec Sodium? The pain severity was assessed using VAS scale at categorically unique times. Data was then analyzed using SPSS 23 version and the results were compiled in the form of mean and percentage. Results: The mean age (Years) of patients was (25.27±6.07). There was a big statistical difference between the 2 groups regarding pain score after the intervention (p=0.018). Conclusion: To reaffirm the effectiveness of Diclofenac for Post-Caesarean section, the physique part (Suppository) is established to hold advantages over the contractile organ (muscles).

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Section: Introductionmentioning

confidence: 99%

To compare efficacy of Diclofenac by intramuscular route and rectal route in post surgical pain.

Zulfiqar¹,

Ashraf²,

Khan³

et al. 2021

TPMJ

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The Use of Rectal Diclofenac Sodium Versus Intravenous Paracetamol for Post Cesarean Section Analgesia

Ismael¹,

Nasir²

2019

JSMC

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Background Pain management is one of the most important aspects of postoperative care. Pain causes unpleasant experiences such as prolongation of postoperative recovery and development of stress reactions. Pain relief is of great importance in patients with Cesarean section by relaxing the mother, enhancing the ability of self-care, resulting into early discharge and subsequently reduces nosocomial infections and hospitalization costs. Objectives To compare the analgesic efficacy of Diclofenac sodium suppository (100 mg) versus intravenous paracetamol (1000 mg) in postoperative pain management for women undergoing Caesarean section. Patients and Methods This study is a single blinded randomized clinical trial conducted in Sulaimani Maternity Teaching Hospital from 1st of June 2018 to 1st of February 2019 on 124 pregnant women who underwent 1st or 2nd Caesarean section under spinal anesthesia without any medical disease or drug allergy. After obtaining informed consent from the participants, patients were randomly divided into two groups. Group A (62 patients) received 100 mg rectal Diclofenac sodium, Group B (62 patients) received 1000 mg intravenous Acetaminophen immediately after cesarean section. The patients were observed for 12 hours after the end of surgery. The pain intensity was judged using McGill pain scale at time periods 1, 6 and 12 hours after the ending of surgery. Results Mean pain score was significantly lower at 1, 6 and 12 hours of Diclofenac sodium group comparing to that of paracetamol group p<0.001. After 1 hour, 60 patients (96.8%) in Diclofenac group had no pain, while 26 of paracetamol group (41.9%) had no pain The paracetamol group significantly needed more additional analgesia than Diclofenac group P<0.001. No side effects were recorded in any of the two groups. Conclusion For post Cesarean pain relief, rectal Diclofenac sodium was found to be safe and effective and has much better analgesic effect than intravenous paracetamol infusion.

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Comparing the Efficacy of Postoperative Diclofenac Suppository with Intramuscular Diclofenac in Children under going Inguinal Hernia Surgery

2020

JMPB

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Objective: To compare the analgesic effect of postoperative Diclofenac suppository with intramuscular Diclofenac in children undergoing inguinal hernia surgery. Methodology: This study was held in Paeds Surgery Department, Nishtar Hospital Multan, Bahawal Victoria hospital Bahawalpur. from August 2018 to March 2019. Total no. of 160 patients were divided into two groups, one receiving diclofenac suppository group DS and the other which was group DI received intramuscular diclofenac injection. Numerical variables like age and weight were analyzed statistically by taking their mean and standard deviation while the outcome variable i.e. severity of pain was assessed through facial expressions as no pain, mild, moderate and severe pain in frequency percentage at 0, 2 and 4 hours interval. Results: Total 160 patients were divided into 2 groups equally, 80 in each (DS & DI). There was no significant difference in the efficacy of diclofenac suppository and diclofenac intramuscular when calculated at 0, 2 and 4 hours interval. When Chi-Square was applied to determine the association, it was observed that pain severity was significantly associated with age. But the association of pain severity with weight and with time intervals in two groups was not statistically significant. Conclusion: From this study we conclude that there is no significant difference between the postoperative analgesic effect of either suppository or intramuscular diclofenac but suppository route has an advantage over intramuscular in that it is easier and safer, less prone to injury, easy to administer and has longer duration of action, especially preferable in pediatric patients.

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Effect of small dose intermittent IV pethidine in combination with diclofenac for post operative pain relief

Cited by 3 publications

References 23 publications

To compare efficacy of Diclofenac by intramuscular route and rectal route in post surgical pain.

To compare efficacy of Diclofenac by intramuscular route and rectal route in post surgical pain.

The Use of Rectal Diclofenac Sodium Versus Intravenous Paracetamol for Post Cesarean Section Analgesia

Comparing the Efficacy of Postoperative Diclofenac Suppository with Intramuscular Diclofenac in Children under going Inguinal Hernia Surgery

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