Effect of Sleeve Gastrectomy on the Neutrophil-to-Lymphocyte Ratio, the Platelet-to-Lymphocyte Ratio, Platelet Counts, and Mean Platelet Volumes

Aykota, Muhammed Raşid; Atabey, Mustafa; Özgen, Utku; Şimşek, Selda

doi:10.1007/s12262-020-02497-0

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…reported increased MPV levels at 6 months of follow-up. [ 25 , 26 ] In the present study, while there was a mild increase in MPV at 6 months ( P < 0.001), we observed that MPV levels remained unchanged at the end of the 1 st year ( P = 0.9).…”

Section: Discussionsupporting

confidence: 43%

Effect of laparoscopic sleeve gastrectomy on platelet count and mean platelet volume

Şen

Oray

Çalıkoğlu

et al. 2023

Journal of Minimal Access Surgery

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Objective: Several studies have reported an increase in platelet (PLT) count with chronic inflammation in the presence of obesity. Mean platelet volume (MPV) is an important marker for PLT activity. Our study aims to demonstrate if laparoscopic sleeve gastrectomy (LSG) has any effect on PLT, MPV and white blood cells (WBCs). Methods: A total of 202 patients undergoing LSG for morbid obesity between January 2019 and March 2020 who completed at least 1 year of follow-up were included in the study. Patients’ characteristics and laboratory parameters were recorded preoperatively and were compared in the 6th and 12th months. Results: Two hundred and two patients (50% – female) with a mean age of 37.5 ± 12.2 years and mean pre-operative body mass index (BMI) of 43 (34.1–62.5) kg/m2 underwent LSG. BMI regressed to 28.2 ± 4.5 kg/m2 at 1 year after LSG (P < 0.001). The mean PLT count, MPV and WBC during the pre-operative period were 293.2 ± 70.3 103 cells/mL, 10.22 ± 0.9 fL and 7.8 ± 1.9 103 cells/mL, respectively. A significant decrease was seen in mean PLT count, with 257.3 ± 54.2 103 cell/mL (P < 0.001) at 1 year post-LSG. The mean MPV was increased at 6 months 10.5 ± 1.2 fL (P < 0.001) and remained unchanged at 1 year 10.3 ± 1.3 fL (P = 0.9). The mean WBC levels were significantly decreased with 6.5 ± 1.7 103 cells/mL (P < 0.001) at 1 year. At the end of the follow-up, weight loss showed no correlation with PLT and MPV (P = 0.42, P = 0.32). Conclusion: Our study has shown a significant decrease in circulating PLT and WBC levels while MPV remained unchanged after LSG.

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Section: Discussionsupporting

confidence: 43%

Effect of laparoscopic sleeve gastrectomy on platelet count and mean platelet volume

Şen

Oray

Çalıkoğlu

et al. 2023

Journal of Minimal Access Surgery

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“…These markers are easily obtainable from routine complete blood count (CBC) analyses and provide cost-effective and readily available data for perioperative risk assessment. Recent studies, including those by Aykota et al (2021) and Ertugrul and Kuzu (2019), have demonstrated significant decreases in the NLR value 6-months and 1-year following bariatric procedures such as laparoscopic sleeve gastrectomy, correlating with reductions in BMI. Aykota et al also observed significant changes in the platelet-to-lymphocyte ratio (PLR) value 1-year after surgery, adding further insight into the role of these markers in tracking long-term surgical outcomes and patient recovery [22,23].…”

Section: Introductionmentioning

confidence: 99%

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Alsabani,

Alenezi,

Alotaibi

et al. 2024

Medicina

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Background and Objectives: This study aimed to investigate the role of the pre- and postoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting intensive care unit (ICU) admission and postoperative length of stay (LOS) in bariatric surgery. Materials and Methods: We retrospectively analysed 96 patients who underwent bariatric surgery at our institution. The NLR and PLR were calculated in the pre- and postoperative stages. Changes in pre- and postoperative hematological ratios were compared using the Wilcoxon signed-rank test. The optimal cutoff values and area under the curve (AUC) for each ratio were calculated using receiver operating characteristic (ROC) analysis. Multivariate linear regression analysis was used to assess the relationship between each ratio and the postoperative LOS after adjusting for age, sex, and American Society of Anesthesiologists (ASA) score. Results: The median age of our patients was 35.50 years, and 54.2% were male. The preoperative NLR showed a significant increase from 1.44 to 6.38 postoperatively (p < 0.001). The PLR increased from 107.08 preoperatively to 183.58 postoperatively, p < 0.001). ROC analysis showed that the postoperative NLR was a moderate to high predictor of ICU admission (AUC = 0.700, optimal cutoff point = 5.987). The postoperative PLR had less predictive power for ICU admission (AUC = 0.641, optimal cutoff point = 170.950). Ratios that had a statistically significant relationship with the postoperative LOS were the preoperative NLR (standardized β [95% CI]: 0.296 [0.115–0.598]), postoperative NLR (0.311 [0.034–0.161]), and postoperative PLR (0.236 [0.000–0.005]). Conclusions: The NLR and PLR demonstrated an independent relationship with the postoperative LOS after bariatric surgery and the predictive ability of ICU admission. Both ratios might be useful as simple markers to predict patient outcome after surgery.

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Correlation of Preoperative Prognostic Laboratory Markers with Bariatric Surgery-Related Complications

Arici,

Erol

2024

Bariatric Surgical Practice and Patient Care

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Effect of Sleeve Gastrectomy on the Neutrophil-to-Lymphocyte Ratio, the Platelet-to-Lymphocyte Ratio, Platelet Counts, and Mean Platelet Volumes

Cited by 3 publications

References 27 publications

Effect of laparoscopic sleeve gastrectomy on platelet count and mean platelet volume

Effect of laparoscopic sleeve gastrectomy on platelet count and mean platelet volume

Ratios of Neutrophils and Platelets to Lymphocytes as Predictors of Postoperative Intensive Care Unit Admission and Length of Stay in Bariatric Surgery Patients: A Retrospective Study

Correlation of Preoperative Prognostic Laboratory Markers with Bariatric Surgery-Related Complications

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