Effect of sleep stages on measurements of passive respiratory mechanics in infants with bronchiolitis

Pulmonary mechanics measurements by respiratory inductive plethysmography and esophageal manometry: Methodology for infants on non-invasive respiratory support

“…The mean (±SD) intra-subject coefficient of variation (CV) between the RIP and PNT methods in this study was 4.6 ± 3.5% (range 0.03% to 13.8%) for C L ; and 3.4 ± 2.2% (range 0.29% to 10.3%) for R L . This level of variability is comparable to, or less than, observations in previous studies on infant pulmonary mechanics measurements and has been attributed to many factors, including: body positioning, sleep state or degree of arousal, timing of feeds, lung volume and degree of chest wall distortion, as well as methodological factors [35][36][37]. In nine low birth weight infants not on any ventilatory support, Ratjen and Wiesemann reported an intra-subject CV for C L ranging from 18% to 47% on repetitions of 8-10 measurements per infant over a mean period of one hour.…”

Exploring the efficacy of using hypertonic saline for nebulizing treatment in children with bronchiolitis: a meta-analysis of randomized controlled trials

“…Sleep quality is relatively important for children's mental and physical development [13][14][15]. This is the first study to analyze sleep quality (including sleep time and frequency of waking up at night) in children with bronchiolitis undergoing nebulizing treatment.…”

“…In case of severe nasal congestion, a child might resort to open-mouth breathing and prone to dyspnea caused by tracheal obstruction, which may cause respiratory failure in severe cases [10,11]. Infants may be prone to vomit due to frequent coughing at night that affect their sleeping quality, day time activities and mental status as well as recovery of the body's immune system [12][13][14][15].…”

Exploring the Efficacy of Using Hypertonic Saline for Nebulizing Treatment in Children with Bronchiolitis: a Meta-Analysis of Randomized Controlled Trials

“…[11][12] Infants may also be prone to vomiting milk due to frequent coughing during the night, which can affect their sleep quality, and in turn affect their activity and mental status during the day and is also closely related to recovery of the body's immune system. [13][14][15][16] Approximately 50 Usually, normal saline is employed as the diluent in nebulizers; the principle is that it uses oxygen flow to vaporize water molecules or drugs and allow these to be breathed in through the mouth and nose and spread to the respiratory tract and lungs with the airflow. After the alveolar capillaries absorb the molecules, the drugs then dilute the secretions in the respiratory tract, induce expectoration, and relieve symptoms of bronchospasm.…”