Effect of sildenafil on erectile dysfunction in spinal Cord injured patients

Treating Erectile Dysfunction and Central Neurological Diseases with Oral Phosphodiesterase Type 5 Inhibitors. Review of the Literature

“…Two clinical studies were excluded because a single dose of sildenafil 50 mg was used once to see the effect on ED, and the other simply to determine the side effects of the drug on SCI patients with ED [21,22]. Regarding the reliability of the studies, one article was excluded because the authors did not report the dosage of sildenafil used for treating individuals with SCI and ED, and there was a possible bias based on the fact that 10 out of the 16 were concomitantly treating their ED with intracavernous alprostadil injection [23].…”