Effect of silane coupling agent treated bovine bone based carbonated hydroxyapatite on in vitro degradation behavior and bioactivity of PLA composites

Rakmae, Suriyan; Ruksakulpiwat, Yupaporn; Sutapun, Wimonlak; Suppakarn, Nitinat

doi:10.1016/j.msec.2012.04.022

Cited by 52 publications

(40 citation statements)

References 40 publications

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“…The existence of CO 3 2-is known to enhance both the solubility and the mechanical strength of HAP. Many researches have consistently revealed that CHAP typically shows superior bioactivity, cytocompatibility, and, if porous, osteoconduction in vivo [31][32][33][34]. The FTIR spectra shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

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Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

et al. 2014

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This work elucidated the antibacterial efficacy, corrosion resistance, and cytotoxicity of electroplated copper-substituted hydroxyapatite (CuHAP) coating on titanium (Ti). The fabricated CuHAP coatings were characterized by scanning electron microscopy, energydispersive X-ray analysis spectroscopy, Fourier transform infrared spectroscopy, and X-ray diffraction studies. The CuHAP coating had needle-like apatite crystals, the doping of Cu 2? into HAP reduced porosity, and the coating became denser. The CuHAP crystals were carbonated with a few of Cu 2? incorporation (about 0.80 wt%). The Cu 2? ions were homogenously deposited into HAP films. Potentiodynamic polarisation test revealed that the CuHAP coating provided good barrier characteristics and achieved superior corrosion protection for Ti substrates. The in vitro antibacterial activity of asprepared CuHAP coating was evaluated against Escherichia coli and was found to be effectively high against bacterial colonization. Bioactivity test conducted by soaking the coatings in simulated body fluid demonstrated that CuHAP coating can quickly induce bone-like apatite nucleation and growth. In vitro biocompatibility tests, MTT, were employed to assess the cytotoxicity of Cu-HAP coating with osteoblast-like MC3T3-E1 cells. The obtained HAP coating doped with a low content of Cu 2? exhibited good cytocompatibility and had no toxicity toward MC3T3-E1.

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Section: Resultsmentioning

confidence: 99%

“…As compared with HAP, CHAP has superior biocompatibility, osteoconductivity, bone-bonding ability, and cell adhesion and proliferation [31]. Melville et al [33] found an equal or even better cell adhesion and proliferation on sintered CHAP compared to a HAP reference.…”

Section: In Vitro Bioactivity Responsesmentioning

confidence: 99%

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

et al. 2014

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“…HA can be synthetically prepared or derived from natural sources, e.g., coral, bovine bone [11][12][13][14][15][16] . Because human bone consists of non-stoichiometric HA with traces of various ions, e.g., HPO 2À 4 , CO 2À 3 , Mg 2þ , Na þ , Fe 2þ , F À , Cl À , which help promoting biocompatibility and bonebonding ability of the materials, several HA preparation techniques have been developed to imitate the natural bone [18,19] .…”

Section: Please Scroll Down For Articlementioning

confidence: 99%

Influence of Heat-Treated Bovine Bone-Derived Hydroxyapatite on Physical Properties andin vitroDegradation Behavior of Poly (Lactic Acid) Composites

Rakmae

Lorprayoon

Ekgasit

et al. 2013

Polymer-Plastics Technology and Engineering

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In this work, nano-size HA was produced from bovine bone. At various heat treatment temperatures, poorly crystalline, partially crystalline and crystalline forms of HA were obtained. PLA composites were prepared by incorporating various forms and contents of HA into PLA matrix. The characteristics of the obtained HA powders affected properties of PLA composites including mechanical properties, morphologies, PLA molecular weight, in vitro bioactivity and in vitro degradation behaviors of the composites. In the case of in vitro bioactivity study, all composites illustrated the induction of bone-like calcium phosphate compounds on their surfaces, especially the PLA/a-HA composites.

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“…Silane coupling agents such as 3-aminopropyltriethoxysilane (KH550), γ-glycidoxypropyltrimethoxysilane (KH560), and g-methacryloxypropyltrimethoxysilane (KH570) have been widely used (Pilla et al 2008;Pilla et al 2009;Chen et al 2010;Wang et al 2011;Zhong et al 2011;Yu et al 2012) and have also been applied in PLA and inorganic composites (Rakmae et al 2012) with natural fillers, such as coconut shell powder (Chun et al 2012), kenaf fiber (Huda et al 2008), cellulose fiber (Frone et al 2011), and wood flour (Pilla et al 2009). Silane coupling agents can be hydrolyzed to produce silanol groups that interact with the filler (Dupraz et al 1996;Zhang et al 2005;Pilla et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Modification of Lignin with Silane Coupling Agent to Improve the Interface of Poly(L-lactic) Acid/Lignin Composites

Zhu¹,

Xue²,

Wei³

et al. 2015

BioResources

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To improve the mechanical properties of lignin-filled poly(L-lactic) composites, three silane coupling agents, 3-aminopropyltriethoxysilane (KH550), γ-glycidoxypropyltrimethoxysilane (KH560), and g-methyacryloxypropyltrimethoxysilane (KH570), were treated systematically with different solvents to modify the interfacial connections. The treatment of lignin with 2 wt.% aqueous KH550 solution was proved to be the most successful. Chemical bonding between the filler and the matrix was formed, according to the FTIR spectra. Furthermore, scanning electron microscope images showed that such treated lignin particles dispersed well in the composites. The tensile strength and Young's modulus of the composite improved significantly from 55.1 and 1589 MPa to 67.0 and 1641 MPa, respectively, with 5 wt.% treated lignin addition. Although its elongation at break decreased from 20.3 to 12.4% after 5 wt.% of the treated lignin was added, it was still better than that of poly(L-lactic acid) without any additive (10.3%).

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Effect of silane coupling agent treated bovine bone based carbonated hydroxyapatite on in vitro degradation behavior and bioactivity of PLA composites

Cited by 52 publications

References 40 publications

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

Influence of Heat-Treated Bovine Bone-Derived Hydroxyapatite on Physical Properties andin vitroDegradation Behavior of Poly (Lactic Acid) Composites

Modification of Lignin with Silane Coupling Agent to Improve the Interface of Poly(L-lactic) Acid/Lignin Composites

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