Effect of shunt type on rates of tube-cornea touch and corneal decompensation after tube shunt surgery in uveitic glaucoma

Sinha, Sapna; Ganjei, Allen Y; Ustaoglu, Melih; Syed, Zeba A.; Lee, Daniel; Myers, Jonathan S.; Fudemberg, Scott J.; Razeghinejad, Reza

doi:10.1007/s00417-021-05095-2

Cited by 4 publications

(4 citation statements)

References 41 publications

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“…In addition to tube-related factors, other factors can influence corneal ECD, including age, toxicity from glaucoma medication, high preoperative IOP, longer duration of high IOP before surgery, higher number of previous intraocular surgeries, and history of uveitis [ 23 ]. Differences in ECD reduction have been reported according to the type of glaucoma, wherein eyes with angle closure glaucoma and pseudoexfoliation glaucoma showed significantly decreased ECD [ 24 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

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Effect of guided Ahmed glaucoma valve implantation on corneal endothelial cells: A 2-year comparative study

Chey

Lee

2023

PLoS ONE

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Purpose To compare the effects of guided and non-guided Ahmed glaucoma valve (AGV) implantation on the corneal endothelium. Methods Medical records of patients who underwent AGV implantation in the anterior chamber (AC) were reviewed retrospectively. The eyes were divided into two groups depending on the use of a guidance technique with spatula and a 4–0 nylon intraluminal stent. Specular microscopy was performed to measure corneal endothelial cell density (ECD) loss after surgery, and the rate of ECD change was calculated. Tube parameters were measured using anterior segment optical coherence tomography (AS-OCT). Results The ECD loss during 2 years of follow-up was significantly lower in the guided AGV implantation (gAGV) group than in the non-guided implantation (ngAGV) group, and the rate of ECD change was -0.62 ± 1.23 and -1.42 ± 1.57%/month in the gAGV and ngAGV groups, respectively (p = 0.003). The mean tube–cornea distance (TCD) and mean tube–cornea angle (TCA) were significantly greater in the gAGV group than in the ngAGV group. The frequency of tube repositioning within 2 years after surgery was 0% in the gAGV group and 12.66% in the ngAGV group (p = 0.005). Conclusions The use of a guidance technique can reduce corneal endothelial loss during the first 2 years after AGV implantation in the AC. The tube was positioned at a more distant and wider angle from the cornea in the eyes of the gAGV group, which may have contributed to the reduced need for tube repositioning to prevent corneal decompensation.

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Section: Discussionmentioning

confidence: 99%

Section: Plos Onementioning

confidence: 99%

Effect of guided Ahmed glaucoma valve implantation on corneal endothelial cells: A 2-year comparative study

Chey

Lee

2023

PLoS ONE

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“…21,22 In addition to tube-related factors, other factors can in uence corneal ECD, including age, toxicity from glaucoma medication, high preoperative IOP, longer duration of high IOP before surgery, higher number of previous intraocular surgeries, and history of uveitis. 23 Differences in ECD reduction have been reported…”

Section: Discussionmentioning

confidence: 99%

Effect of Guided Ahmed Glaucoma Valve Implantation on Corneal Endothelial Cells: A 2-Year Comparative Study

Chey

Lee

2022

Preprint

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Purpose: To compare the effects of guided and non-guided Ahmed glaucoma valve (AGV) implantation on the corneal endothelium.Methods: Medical records of patients who underwent AGV implantation in the anterior chamber (AC) were reviewed retrospectively. The eyes were divided into two groups depending on the use of a guidance technique with spatula and a 4-0 nylon intraluminal stent. Specular microscopy was performed to measure corneal endothelial cell density (ECD) loss after surgery, and the rate of ECD change was calculated. Tube parameters were measured using anterior segment optical coherence tomography (AS-OCT). Results: The ECD loss during 2 years of follow-up was significantly lower in the guided AGV implantation (gAGV) group than in the non-guided implantation (ngAGV) group, and the rate of ECD change was -0.62 ± 1.23 and -1.42 ± 1.57 %/month in the gAGV and ngAGV groups, respectively (p = 0.003). The mean tube–cornea distance (TCD) and mean tube–cornea angle (TCA) were significantly greater in the gAGV group than in the ngAGV group. The frequency of tube repositioning within 2 years after surgery was 0 % in the gAGV group and 12.66 % in the ngAGV group (p = 0.005). Conclusions: The use of a guidance technique can reduce corneal endothelial loss during the first 2 years after AGV implantation in the AC. The tube was positioned at a more distant and wider angle from the cornea in the eyes of the gAGV group, which may have contributed to the reduced need for tube repositioning to prevent corneal decompensation.

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“…The same group reported a greater incidence of corneal complications in BGI compared to AGV. Previous trabeculectomy was considered a risk factor for corneal decompensation [ 115 ].…”

Section: Tube Shunt Surgery In Uveitic Glaucomamentioning

confidence: 99%

Update on Diagnosis and Treatment of Uveitic Glaucoma

Halkiadakis,

Konstantopoulou,

Tzimis

et al. 2024

JCM

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Glaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias in the interpretation of optical coherence tomography measurements. For the successful treatment of UG, the control of intraocular inflammation specific to the cause or anti-inflammatory treatment, combined with IOP management, is mandatory. The early institution of specific treatment improves the prognosis of UG associated with CMV. The young age of UG patients along with increased failure rates of glaucoma surgery in this group of patients warrants a stepwise approach. Conservative and conjunctival sparing surgical approaches should be adopted. Minimally invasive surgical approaches were proved to be effective and are increasingly being used in the management of UG along with the traditionally used techniques of trabeculectomy or tubes. This review aims to summarize the progress that recently occurred in the diagnosis and treatment of UG.

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Effect of shunt type on rates of tube-cornea touch and corneal decompensation after tube shunt surgery in uveitic glaucoma

Cited by 4 publications

References 41 publications

Effect of guided Ahmed glaucoma valve implantation on corneal endothelial cells: A 2-year comparative study

Effect of guided Ahmed glaucoma valve implantation on corneal endothelial cells: A 2-year comparative study

Effect of Guided Ahmed Glaucoma Valve Implantation on Corneal Endothelial Cells: A 2-Year Comparative Study

Update on Diagnosis and Treatment of Uveitic Glaucoma

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