Effect of Selenium, Vitamin E, and Antioxidants on Testicular Function in Rats12

Wu, Shao-Guo; Oldfield, J. E.; Whanger, P. D.; Weswig, P. H.

doi:10.1093/biolreprod/8.5.625

Cited by 144 publications

(56 citation statements)

References 6 publications

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“…Wu et al (1973) reported that the spermatozoa from rats on the basal diet with the addition of both Vit.E (60 ppm) and selenium (0.1 ppm) showed normal morphology and excellent motility. Supplementing the diet of quail with Vit.E and corn oil changed sperm characteristics in the present study favorably, increasing viability, and the sperm concentration with progressive motility and normal morphology.…”

Section: Resultsmentioning

confidence: 99%

The influence of inclusions of vitamin E and corn oil on semen traits of Japanese quail (Coturnix coturnix japonica)

Adabi¹,

Cooper²,

Kamali³

et al. 2011

Animal Reproduction Science

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Reported was an investigation of the effect of vitamin E (Vit.E) and corn oil on semen traits of male Japanese quail (Coturnix coturnix japonica). From 8 to 20 wk of age, birds were raised on corn-based diets supplemented with corn oil (0 and 3%) and Vit.E (National Research Council (NRC) recommended 25 mg/kg/day/dry matter and 150 mg/kg/day/dry matter) in a 2 × 2 factorial manner. The diet was supplemented with corn oil and Vit.E (E2C2) which provided additional n-6 polyunsaturated fatty acids in the form of 20:4n-6 and 22:4n-6 in spermatozoa phospholipid. The left testes weights were increased (P < 0.01) in groups that received Vit.E in the diet (3.95 and 4.12 g, respectively) (P = 0.03) and combined testes weight was the greatest in E2C2 group (7.57 g) (P = 0.02). Semen volume increased throughout the experiment in the E2C2 group. E2C1 and E2C2 birds had the greatest (90.05% and 92.1%, respectively) live sperm percent by comparison with other groups. The susceptibility of semen to lipid peroxidation in vitro was increased in quail fed E1C1 and E1C2, but was reduced when 150 mg Vit.E kg/day/dry matter feed was provided in the diet. The amount of Vit.E in the seminal plasma of E1C1 and E1C2 groups was (P < 0.01) less than that in the other two groups (E2C1 and E2C2). From this study, it may be concluded that increasing diet n-6/n-3 ratio can be beneficial for semen traits, however, this application increased sperm peroxidation sensitivity but it can be controlled by inclusion of antioxidant such as Vit.E (150 mg/kg/day/dry matter) to diet.

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Section: Resultsmentioning

confidence: 99%

The influence of inclusions of vitamin E and corn oil on semen traits of Japanese quail (Coturnix coturnix japonica)

Adabi¹,

Cooper²,

Kamali³

et al. 2011

Animal Reproduction Science

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show abstract

“…31 Se concentration of seminal plasma correlated positively with concentration of spermatozoa in a group of sub-fertile Norwegian men. 32 Animals fed Se-deficient diets show structural abnormalities in the sperm midpiece which are linked to poor motility and a tendency for the tail to break off 33 thus decreasing the chance of fertilisation. An explanation for these findings has recently been afforded by the work of Ursini and colleagues.…”

Section: Reproductionmentioning

confidence: 99%

The importance of selenium to human health

2000

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“…VE deficiencies caused testicular degeneration in poultry (Todorovic et al, 2002), rat and hamster (Sidney et al, 1975) and resulted in a lower number of germ cells and a reduction in sperm production (Cooper et al, 1987). Wu et al (1973) and Wilson et al (2003) found deficiency of VE may lead to reproductive organ damage, such as degenerative spermatogonium, testicular damage and degeneration of the seminiferous tubules. In view of the above, VE can reduce the oxidative damage on reproductive organs and the effects of VE on reproductive efficiency have been described in several species.…”

Section: Introductionmentioning

confidence: 99%