Effect of secondary attack by Aeromonas hydrophila on the expression level of hif genes in common carp (Cyprinus carpio)

Abstract

Hypoxia-inducible factors (hifs), which are a class of nuclear transcriptional complexes that mediate the cellular responses to hypoxia, are composed of α and β subunits. The α subunit is an oxygen response element that functions as a regulator (Marcin et al., 2018;Prabhakar & Semenza, 2012). There are three subtypes of hifα that are adapted to the complex hypoxic response, hif1α,