Effect of <scp>QMix</scp> as final irrigation protocol on periapical healing after single‐visit root canal treatment: A randomised controlled clinical trial

Uçan, Cemre Sapmaz; Dumani, Ayşin; Ünal, İlker; Yılmaz, Şehnaz; Yoldaş, Oğuz

doi:10.1111/aej.12701

Cited by 6 publications

(3 citation statements)

References 31 publications

(41 reference statements)

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“…QMix demonstrated a high capability of removing the smear layer and eradicating E. faecalis, high wettability, favorable surface tension properties, and biocompatibility, which, in several reports, demonstrated superior antimicrobial effects when compared in vitro to sodium hypochlorite and chlorhexidine [165 -167]. In a recent randomized clinical trial, however, the use of QMix irrigation solution as a final rinse resulted in no significant difference in periapical healing compared to sodium hypochlorite alone at the end of a one-year follow-up period [168].…”

Section: Qmixmentioning

confidence: 99%

Antimicrobial Irrigation Solutions in Root Canal Treatment: A Glance at the Past, the Present, and the Future

Qutieshat,

Al Harthy,

Al Busaidi

et al. 2023

TODENTJ

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Background: Many current concepts about irrigation solutions have evolved over time; a historical perspective of irrigation solutions and the reasons for their introduction to endodontic treatment is required. The authors of this work believe that a large number of unrecognised published works from the 20th century need to be brought to light so that researchers can acquire some important hints and insights into how those solutions were developed and used in the past. In this paper, we investigate historical attempts to develop the optimal irrigation solution as well as the evolution of the scientific community's views on how to achieve this aim. Methods: A review of the literature related to irrigation solutions in endodontics was conducted using Scopus, Google Scholar, and Web of Science. Historical articles were identified through tracking citations of included articles and were obtained via the library of the University of Dundee. Results: Without the attempts of the past, we wouldn't be where we are today, including the role that several irrigation solutions played in endodontics before they were phased out. The observation that none of the currently available solutions had all of the properties that would make them ideal when used on their own led to the conception of the notion of mixing multiple types of irrigation systems, an idea that has since become widely popular. Conclusion: This study suggests pursuing two lines of inquiry: first, finding the best companion to sodium hypochlorite that produces no undesirable reaction precipitates; and second, maintaining the effort toward the development of a single irrigation solution that can effectively disinfect the canal without endangering the vital tissues. In general, and for some different possible combinations, there appears to be some light at the end of the tunnel, which is something that will hopefully be uncovered in the not-too-distant future.

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Section: Qmixmentioning

confidence: 99%

Antimicrobial Irrigation Solutions in Root Canal Treatment: A Glance at the Past, the Present, and the Future

Qutieshat,

Al Harthy,

Al Busaidi

et al. 2023

TODENTJ

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“…Interestingly, clinical studies comparing combined irrigants did not report statistically significant differences in reducing bacterial counts (Ballal, Gandhi, et al, 2019;Ballal, Jain, et al, 2019;Malkhassian et al, 2009), unless Tandon et al (2022). Also, in a recent clinical study (Sapmaz et al, 2023), QMix was found inferior to NaOCl irrigation in single-rooted teeth with apical periodontitis in terms of periapical healing after singlevisit root canal treatment.…”

Section: Introductionmentioning

confidence: 97%

“…Although several in vitro studies investigated these combined irrigants' biocompatibility, and antimicrobial and smear layer removal properties (Ballal et al, 2023; Ballal, Jain, et al, 2019; Johal et al, 2007; Torabinejad, Cho, et al, 2003; Torabinejad, Khademi, et al, 2003; Torabinejad, Shabahang, et al, 2003), very few clinical studies have been conducted with these irrigants (Ballal, Gandhi, et al, 2019; Malkhassian et al, 2009; Sapmaz et al, 2023; Torabinejad et al, 2005). Interestingly, clinical studies comparing combined irrigants did not report statistically significant differences in reducing bacterial counts (Ballal, Gandhi, et al, 2019; Ballal, Jain, et al, 2019; Malkhassian et al, 2009), unless Tandon et al (2022).…”

Section: Introductionmentioning

confidence: 99%

Outcome of single‐visit root canal treatment with or without MTAD: A randomized controlled clinical trial

Yildiz,

Dumani,

Isci

et al. 2023

Int Endodontic J

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AimThis study aimed to investigate 2‐year changes in periapical trabecular patterns in single‐rooted teeth with apical periodontitis using fractal analysis and periapical index (PAI) after root canal treatment performed with or without BioPure MTAD solution.MethodologyIn this randomized clinical trial, 100 patients were selected and randomized to either the BioPure MTAD or the control groups. Initial periapical radiographs were obtained for each participant before and 2 years after root canal treatment. The region of interest in the periapical lesion around the root apex was selected from the paired periapical radiographs, and then, the fractal dimension (FD) was calculated. With regards to the classification of periapical status, PAI was labelled as “healed” (PAI ≤ 2) or “unhealed” (PAI ≥ 3).ResultsAfter 24 months, 28 patients did not comply with the follow‐up and the data of 72 patients were compared. When the initial and the follow‐up PAI scores were compared, the decrease was statistically significant in 33 of 37 teeth (89.2%) and 32 of 35 teeth (91.4%) in the BioPure MTAD and control group, respectively. In both groups, statistically significant increases were observed in FD values after 2 years in all patients (p < .001). No significant difference was found between the two groups amongst decreased PAI scores and increased FD values.ConclusionsRoot canal treatments with or without BioPure MTAD irrigation contributed to periapical healing in single‐visit root canal treatment. Two years after root canal treatment, the extent of the periapical trabecular bone radiographically increased, as the FD and PAI data revealed.

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The effect of ascorbic acid, QMix and other conditioning solutions on the bond strength of adhesively luted glass fiber-reinforced composite posts to root dentin, a laboratory study

Albashaireh,

Taha,

Albashaireh

2024

Journal of Dentistry

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Effect of QMix as final irrigation protocol on periapical healing after single‐visit root canal treatment: A randomised controlled clinical trial

Cited by 6 publications

References 31 publications

Antimicrobial Irrigation Solutions in Root Canal Treatment: A Glance at the Past, the Present, and the Future

Antimicrobial Irrigation Solutions in Root Canal Treatment: A Glance at the Past, the Present, and the Future

Outcome of single‐visit root canal treatment with or without MTAD: A randomized controlled clinical trial

The effect of ascorbic acid, QMix and other conditioning solutions on the bond strength of adhesively luted glass fiber-reinforced composite posts to root dentin, a laboratory study

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