Effect of anti‐VEGF on retinal blood flow in diabetic mice using laser speckle flowgraphy
Zheng Zhe Steven Su,
Bryan Chin Hou Ang,
Praveen Kumar Balne
et al.
Abstract:PurposeTo assess intra‐ (repeatability) and inter‐observer (reproducibility) variability of laser speckle flowgraphy (LSFG) for retinal blood flow (RBF) measurement in 20 eyes of wild type (C57BL/6J) mice and effect of intravitreal Aflibercept on RBF in optic nerve head (ONH) region of 10 eyes of Ins2 (Akita) diabetic mice.Methods‘Mean blur rate (MBR)’ was measured for all quadrants of tissue area (MT), vessel (MV) and total area (MA) of ONH region. Changes in MT were analysed at each timepoint. Repeatability … Show more
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