The aim of this research project is to improve current practice by investigating different test methods to quantify moisture damage to serve the short-and longterm needs of the agency and industry. This research deals with important concepts of stripping as, bitumen chemistry and rheology, aggregate properties (chemical and mineralogical composition, surface texture, morphology, porosity, etc.), traffic, water properties, construction practices (mixing, placement and in-service drainage) and nature of antistripping additives. This paper presents the effect of anti-stripping additives in bituminous mixes. As per researches series of laboratory tests have been conducted with varying percentage of these Anti-stripping additives, added Individually and in Combinations, to determine their optimum percentages. This report presents the results of experimental investigations carried out to study the effect of Wetbond-S, Zycotherm and Bitugrip on bitumen and aggregate. Boiling water test and Stripping value test were conducted as screening tests performed on Wetbond-S, Bitugrip and Zycotherm modified bitumen. The current research shows the optimization of different anti-stripping additives to evaluate moisture susceptibilities of bituminous mixes. This paper deals with the review of some previous studies that are done to improve the adhesion between bitumen and aggregate.The stripping value decreases while increasing the percentage of anti-stripping additives to the bitumen. The results indicated that the addition of anti-stripping agents increase moisture resistance of asphalt mixes to some extent. Moreover, it was concluded that mix samples prepared using anti-stripping additive imparted more correlation and greater resistance to water damage.