Effect of S53P4 bioactive glass content on structural and in-vitro behavior of hydroxyapatite/bioactive glass mixtures prepared by mechanical milling

Forero-Sosa, P.A.; Salazar-Martinez, J.D.; Barajas-Aguilar, V.J.; Olvera-Alvarez, I.U.; Henao, John; Espinosa-Arbeláez, D.G.; Trápaga-Martínez, G.; Giraldo-Betancur, Astrid L.

doi:10.1016/j.ceramint.2022.09.317

Cited by 5 publications

(1 citation statement)

References 57 publications

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“…In addition, it was noticed that the addition of BG S53P4 increases the hydroxyapatite formation. It is known that the presence of Si ions from BG S53P4 in calcium phosphates materials facilitates the hydroxyapatite formation in the scaffold surface [56]. Pietak et al 2007 studied the substitution of Si ions in calcium phosphate materials and found that Si ions have facilitated the obtention of hydroxyapatite on the calcium phosphate surface and increased their biological activity [57].…”

Section: Apatite Mineralization Ability Of the β-Tcp And β-Tcp/s53p4 ...mentioning

confidence: 99%

3D Printing of β-TCP/S53P4 Scaffolds: Physicochemical, Mechanical, and Biological in vitro Evaluation

Alves

Barbosa

Oliveira

et al. 2023

J. Mater. Sci. Technol. Res.

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The focus of bone tissue engineering is on the new strategies for developing bioactive and resorbable scaffolds, which have become an alternative to the treatment of bone diseases and trauma. β-tricalcium phosphate (β-TCP) is considered resorbable and has excellent osteoconductivity. In an attempt to achieve good densification of the β-TCP scaffold and improve its biological properties, it arises the possibility of combining this material with S53P4 bioactive glass. Several techniques are used to produce bioceramic scaffolds, among them, direct ink writing (DIW) a type of additive manufacturing based on material extrusion, which allows the production of customized parts, with high complexity and good reproducibility. This work prepared β-TCP and β-TCP/S53P4 (β-TCP/10-S53P4 = 10% wt of S53P4 and β-TCP/20-S53P4 = 20% wt of S53P4) scaffolds by DIW. The ceramic inks showed pseudoplastic behavior and the 3D-printed scaffolds showed similar aspects to the digital model. Also, the β-TCP/S53P4 scaffolds (β-TCP/10-S53P4 = 1.6 ± 0.6 MPa and β-TCP/20-S53P4 = 2.1 ± 0.9 MPa) showed an increase in compressive strength when compared to β-TCP scaffolds (0.9 ± 0.1 MPa). All scaffolds showed apatite-mineralization ability in SBF after soaking for 7 and 14 days, being that the β-TCP/20-S53P4 scaffold showed a higher ability of apatite formation compared to the other scaffolds. Concerning the biological in vitro assays, all the scaffolds showed good cell viability. Thus, the β-TCP/S53P4 scaffolds showed adequate properties which become them, good candidates, to be used in bone tissue engineering.

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Section: Apatite Mineralization Ability Of the β-Tcp And β-Tcp/s53p4 ...mentioning

confidence: 99%

3D Printing of β-TCP/S53P4 Scaffolds: Physicochemical, Mechanical, and Biological in vitro Evaluation

Alves

Barbosa

Oliveira

et al. 2023

J. Mater. Sci. Technol. Res.

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show abstract

HVOF-sprayed HAp/S53P4 BG composite coatings on an AZ31 alloy for potential applications in temporary implants

Poblano-Salas,

Henao,

Giraldo-Betancur

et al. 2024

Journal of Magnesium and Alloys

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Preparation of hydroxyapatite/bioactive glass/collagen scaffolds for use in tissue engineering

Gomes

Santos

Dumont

et al. 2023

Journal of Non-Crystalline Solids

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Effect of S53P4 bioactive glass content on structural and in-vitro behavior of hydroxyapatite/bioactive glass mixtures prepared by mechanical milling

Cited by 5 publications

References 57 publications

3D Printing of β-TCP/S53P4 Scaffolds: Physicochemical, Mechanical, and Biological in vitro Evaluation

3D Printing of β-TCP/S53P4 Scaffolds: Physicochemical, Mechanical, and Biological in vitro Evaluation

HVOF-sprayed HAp/S53P4 BG composite coatings on an AZ31 alloy for potential applications in temporary implants

Preparation of hydroxyapatite/bioactive glass/collagen scaffolds for use in tissue engineering

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