Effect of Routine Clopidogrel Use on Bleeding Complications After Endobronchial Ultrasound-guided Fine Needle Aspiration

Webb, Tracey N.; Flenaugh, Eric; Martin, R.C.G.; Parks, Christopher; Bechara, Rabih

doi:10.1097/lbr.0000000000000493

Cited by 9 publications

(3 citation statements)

References 24 publications

(35 reference statements)

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“…The study by Webb et al 11 adds to the emerging data on EBUS-TBNA safety, reassuring us that, in the hands of expert bronchoscopists, this procedure can indeed be performed safely on patients receiving antiplatelet therapy. Although there is a collective lack of bleeding complications in all studies performed to date, we should still interpret these results with caution.…”

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confidence: 93%

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EBUS-TBNA on Patients Receiving Antiplatelet Therapy

Zouk

Michaud²

2019

Journal of Bronchology &Amp; Interventional Pulmonology

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confidence: 93%

“…In the current issue of The Journal of Bronchology and Interventional Pulmonology, Webb et al 11 present their experience performing EBUS-TBNA on patients on both aspirin and clopidogrel. In this multicenter prospective study, the authors included all subjects presenting with mediastinal or hilar lymphadenopathy requiring sampling for staging and/or diagnosis.…”

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confidence: 99%

EBUS-TBNA on Patients Receiving Antiplatelet Therapy

Zouk

Michaud²

2019

Journal of Bronchology &Amp; Interventional Pulmonology

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“…However, the management of ATAs before and after EBUS-TBNA has not yet been well understood. Several previous studies have shown that EBUS-TBNA could be performed safely in patients taking clopidogrel, but these studies were based on small numbers of cases [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Effects of Antithrombotic Treatment on Bleeding Complications of EBUS-TBNA

Gil

Lee

et al. 2021

Medicina

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Background and Objectives: The application of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been markedly increased over the past decade. EBUS-TBNA is known to be a very safe and accurate procedure; however, the incidence of bleeding complications in patients who are taking antithrombotic agents (ATAs) is not well established. Materials and Methods: We conducted a retrospective analysis of a prospectively registered EBUS-TBNA cohort in a single tertiary hospital from May 2009 to December 2016. The patients were divided into two groups: an insufficient discontinuation group, defined as having a prescription for ATAs on the procedure day or only interrupting them for a short period of time, and a sufficient discontinuation group, defined as having prescription for ATAs during 30 days prior to the procedure and interrupting them for a sufficient period of time. Results: During the study period, a total of 4271 patients, after excluding 3773 patients who did not take ATAs at all, 498 patients were classified into the insufficient discontinuation group (n = 102) and the sufficient discontinuation group (n = 396). The baseline characteristics of patients and examined lesions between two groups were not significantly different, except insufficient discontinuation group had longer prothrombin times than the sufficient discontinuation group. In the insufficient discontinuation group, the most common reasons for prescriptions of ATAs were ischemic heart disease (48.0%) and cerebral vascular disease (28.4%), and half of the patients were taking two or more ATAs. Eventually, only one bleeding complication in the insufficient discontinuation group (1/102, 1.0%) and one event in the sufficient discontinuation group (1/396, 0.3%) occurred (p = 0.368). Conclusions: EBUS-TBNA is considered a safe procedure in terms of bleeding complications, even in patients with insufficient stopping of ATAs.

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Endobronchialer Ultraschall (EBUS)

Darwiche

2024

Flexible Bronchoskopie Für Einsteiger

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Effect of Routine Clopidogrel Use on Bleeding Complications After Endobronchial Ultrasound-guided Fine Needle Aspiration

Abstract: We suggest that EBUS-TBNA, using 22 and 21-G needles, is safe with high yields in patients with mediastinal/hilar adenopathy, actively taking clopidogrel and aspirin, and are at high risk for thrombotic complications if the medication is discontinued.

Cited by 9 publications

References 24 publications

EBUS-TBNA on Patients Receiving Antiplatelet Therapy

EBUS-TBNA on Patients Receiving Antiplatelet Therapy

Effects of Antithrombotic Treatment on Bleeding Complications of EBUS-TBNA

Endobronchialer Ultraschall (EBUS)

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