Effect of Rice Starch as a Bath Additive on the Barrier Function of Healthy but SLS-damaged Skin and Skin of Atopic Patients

Paepe, Kristien De; Hachem, Jean-Pierre; Vanpee, Els; Roseeuw, Diane; Rogiers, Vera

doi:10.1080/00015550260132460

Cited by 26 publications

(17 citation statements)

References 2 publications

(4 reference statements)

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“…Addition of rice starch to bath water was recently shown to improve barrier function in patients with AD. 7 To prevent evaporative effects, which are damaging to the skin barrier, patients need to apply medication or moisturizer immediately after bathing or wetting their skin.…”

Section: Skin Hydration and Moisturizersmentioning

confidence: 99%

Current management of atopic dermatitis and interruption of the atopic march

Boguniewicz

Eichenfield

Hultsch

2003

Journal of Allergy and Clinical Immunology

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Section: Skin Hydration and Moisturizersmentioning

confidence: 99%

Current management of atopic dermatitis and interruption of the atopic march

Boguniewicz

Eichenfield

Hultsch

2003

Journal of Allergy and Clinical Immunology

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“…Current studies demonstrated that skin barrier dysfunction could be responsible for the pathogenesis of AD in a murine model and AD patients [24, 25]. Several studies have shown that treatment with a moisture cream could ameliorate the impairment of the skin barrier function in AD patients [26, 27]. Of interest, the density of S. aureus on the skin of the mice treated with Pet+UVA was lower at 17 weeks compared with that at the beginning of treatment.…”

Section: Discussionmentioning

confidence: 99%

Effects of Photocatalytic Agent on DS-<i>Nh</i> Mice, Developing Atopic Dermatitis-Like Eruption with an Increase of <i>Staphylococcus aureus</i>

Kambara

Aihara²,

Matsukura³

et al. 2006

Int Arch Allergy Immunol

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Background:Staphylococcus aureus(S. aureus) is thought to play a significant role in the exacerbation of atopic dermatitis (AD). DS-Nh mice, a non-hair-bearing mouse model of AD, spontaneously develop dermatitis under conventional conditions. A remarkable increase in S. aureus is considered to strongly relate to the induction and aggravation of this dermatitis. A topical use of anatase-type titanium dioxide (TiO₂) followed by UV irradiation, acting as photocatalyst, is believed to have antibacterial activity. We investigated the bactericidal effect of TiO₂ with UV irradiation on DS-Nh mice to prevent the aggravation of the dermatitis. Methods: Ten-week-old DS-Nh mice were treated with TiO₂ in petrolatum on the back, followed by UVA irradiation, for 11 weeks. The severity of dermatitis was assessed by evaluating individual lesions using a 4-grade scale and expressed as the total skin score. S. aureus colonizing the mouse skin was counted after isolation and incubation with agar medium. The skin barrier dysfunction was evaluated by measuring transepidermal water loss (TEWL). Results:The mice treated with TiO₂ and UV irradiation showed a significant increase in total skin scores, the number of S. aureus and TEWL values, compared with non-treated mice. In contrast, these parameters were significantly lower in the mice treated with petrolatum and UV irradiation. Conclusions: A significant increase in S. aureus was recognized on the skin together with the aggravation of AD-like dermatitis in our mice model. Skin barrier dysfunction induced by TiO₂ and UV irradiation seems to facilitate the increase in S. aureus.

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“…A study conducted on volunteer subjects has shown that baths with rice starch can alleviate skin irritation caused by sodium lauryl sulfate (SLS), while they also ameliorate the skin barrier in patients with atopic dermatitis (Fujiwaki and Furusho 1992;De Paepe, Hachem et al 2002). Rice starch is also used in makeup products (Braunagel and Guderjahn 2006).…”

Section: Accepted Manuscriptmentioning

confidence: 98%