Effect of Rice Diet on Diabetes Mellitus Associated With Vascular Disease

Kempner, Walter; Peschel, Ruth Lohmann; Schlayer, C.

doi:10.1080/00325481.1958.11692236

Cited by 52 publications

(22 citation statements)

References 5 publications

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“…Our results support what has been reported of the risk of insulin resistance due to WR consumption . Despite the fact that Kempner et al used WR as part of dietary therapy for metabolic conditions , fruits, and vegetables in his diet may have offset the negative effects of WR . In fact, recently the debate over links between WR and diabetes was reignited .…”

supporting

confidence: 88%

Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice

Imam

Ismail

Ooi

et al. 2014

Molecular Nutrition Food Res

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White rice (WR) is a major staple food for people in developing countries and it may be responsible for the growing incidence of type 2 diabetes. Nonpregnant Female Sprague Dawley rats fed with WR or brown rice (BR) for 8 weeks were mated with age-matched male rats maintained on normal pellet over the same period. Offsprings were fed normal pellet after weaning until 8 weeks postdelivery. Rats fed with WR and their offsprings showed worsened oral glucose tolerance test, lower serum adiponectin levels, and higher weights, homeostatic model assessment of insulin resistance, serum retinol binding protein-4 levels, and leptin levels, compared with the normal and BR groups, suggesting an increased risk of insulin resistance. Furthermore, transcriptional levels of genes involved in insulin signaling showed different expression patterns in the liver, muscle, and adipose tissues of mothers and offsprings in both WR and BR groups. The results propose that the cycle of WR-induced insulin resistance in offsprings due to prenatal exposure, followed by their consumption of WR later in life may contribute to diabetes incidents. These findings are worth studying further.

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supporting

confidence: 88%

Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice

Imam

Ismail

Ooi

et al. 2014

Molecular Nutrition Food Res

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“…They demonstrated, in a relatively small number of insulin-treated patients (probably with type 2 diabetes), that introduction of a high carbohydrate -high fibre diet was associated with a dramatic improvement in glycaemic control and reduction in insulin dose (Kiehm et al, 1976). In fact such observations were not entirely new, similar observations having been made many years earlier by Kempner using his rice diet (Kempner et al, 1958). Inspired by the work of Anderson and also by the studies of Stone and Connor (1963), who drew attention to the potential of the low carbohydrate -high fat diet, then in widespread use, to increase cardiovascular risk, our own group in Oxford, England embarked on a series of carefully controlled studies which helped to further understand the role of dietary fibre (Simpson et al, 1979a;Simpson et al, 1979b;Simpson et al, 1981;Simpson et al, 1982;Lousley et al, 1984;Geekie et al, 1986;Mann, 1984).…”

supporting

confidence: 54%

Dietary fibre and diabetes revisited

Mann¹

2024

Eur J Clin Nutr

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“…46 Plant-based diets may also help prevent 47,48 and treat diabetic retinopathy. Kempner et al 49 were the first to document the reversal of diabetic retinopathy with diet. They found that 30% of participants (13 of 44) on a plant-based diet of mostly rice and fruit showed a marked fundal regression of diabetic hemorrhages, exudates, aneurysms, and retinitis proliferans.…”

Section: Painful Diabetic Neuropathymentioning

confidence: 99%

Plant-Based Diets for the Prevention and Treatment of Disabling Diseases

Greger

2015

American Journal of Lifestyle Medicine

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Overestimates of the efficacy of surgical and pharmacological interventions for the prevention and treatment of chronic disease and underestimates of the associated risks may bias physicians and patients against lifestyle medicine interventions that can be cheaper, safer, and more effective by treating the underlying cause of disease. The leading causes of both death and disability in the United States are diet, followed by smoking. The food and tobacco industries share similar tactics to downplay and obfuscate the risks associated with their products, but physicians can educate themselves about the role lifestyle interventions can play in the prevention and treatment of chronic disease. For example, a diet centered around whole plant foods can be used to successfully treat angina and painful diabetic neuropathy and may help prevent low-back pain and Alzheimer's disease, all perhaps because of a common underlying vascular component. The delay between recognizing the risks of smoking and effective public health measures may have cost millions of lives. Similar delays in stopping dietary diseases may cost millions more.

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Effect of Rice Diet on Diabetes Mellitus Associated With Vascular Disease

Cited by 52 publications

References 5 publications

Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice

Increased risk of insulin resistance in rat offsprings exposed prenatally to white rice

Dietary fibre and diabetes revisited

Plant-Based Diets for the Prevention and Treatment of Disabling Diseases

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