Effect of residues remaining in the injection liner of a gas chromatograph on the quantification of polycyclic aromatic hydrocarbons by isotope dilution mass spectrometry using deuterium-labeled internal standards

Application of amino acid analysis using hydrophilic interaction liquid chromatography coupled with isotope dilution mass spectrometry for peptide and protein quantification

“…In contrast, isotope dilution mass spectrometric amino acid analysis using isotopically labeled amino acids as internal standards is thought to have the smallest achievable uncertainties for analytical measurement [15]. Isotope-dilution mass spectrometry (IDMS) is based on the principle that stable internal standards behave in the same manner as the corresponding target (natural) compounds throughout the hydrolysis and analytical processes [16]. Thus, the recovery problems throughout these processes can be cancelled out by the use of isotope-labeled internal standards.…”

Evaluation of Behavioral Differences between Native Polycyclic Aromatic Hydrocarbons and 13C-Labeled Internal Standards during Clean-up Steps of Analysis

“…GC 13,14 Note that the peak intensity of Per-d12 in the calibration solution, which is used as a criterion in the recovery calculation, is affected by the residue remaining in the injection liner. 14 Thus, the calibration solution was always injected after the samples in this study to obtain a constant peak intensity for Per-d12.…”

Alkaline extraction in combination with microwave-assisted extraction followed by solid-phase extraction treatment for polycyclic aromatic hydrocarbons in a sediment sample

“…GC-MS analysis was carried out with a 6890/5975 system from Agilent Technologies (Palo Alto, CA, USA), equipped with a DB-17MS capillary column (30 m × 0.25 mm, 0.25 m film thickness) (J&W Scientific, Folson, CA, USA) [22,23]. The GC system was operated in the splitless mode and 1-L portions of the extracts were injected by using an autosampler.…”