Effect of renal transplantation on multiple hormone levels in patients of chronic kidney disease: A single center study

Kumar, Rajesh; Jhorawat, Rajesh; Mathur, Mohit; Garsa, Rajesh Kumar; Kimmatkar, Piyush; Sharma, Sanjeev Kumar; Singh, AK; Beniwal, Pankaj; Malhotra, Vinay

doi:10.1016/j.ijt.2014.08.002

Cited by 3 publications

(10 citation statements)

References 16 publications

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“…В исследовании Kumar R. и соавт. (2014) выявлено, что содержание пролактина уменьшилось через 6 мес после трансплантации почки, однако при динамическом наблюдении нарушение функции трансплантата вновь вызывало повышение уровня данного гормона [ 25 ].…”

Section: пролактинunclassified

“…Уменьшение концентрации эстрогенов и тестостерона отягощает течение ХБП и снижает качество жизни пациентов. Проведение диализной терапии в подавляющем большинстве случаев не приводит к нормализации концентрации гонадотропинов [ 25 ]. Применение заместительной гормональной терапии препаратами эстрогенов и тестостерона в данной группе больных ограничено в связи с отсутствием четких клинических рекомендаций, разработанных на основе результатов крупных рандомизированных исследований [ 28 ].…”

Section: гонадотропиныunclassified

“…В настоящее время имеются данные, свидетельствующие о том, что пересадка почки способствует нормализации концентрации гонадотропинов у пациентов с тХБП. Так, спустя 6 мес после трансплантации почек происходит снижение уровней ЛГ и ФСГ [ 25 ][ 38 ], в то же время содержание тестостерона [ 39 ] и эстрогенов [ 38 ] может как повышаться, так и оставаться без существенных изменений [ 25 ][ 39 ].…”

Section: гонадотропиныunclassified

“…Однако данное лечение не показало однозначного преимущества в отношении снижения смертности в изучаемой группе больных, что требует проведения дальнейших клинических исследований [ 44 ]. Нормализация уровня гормонов щитовидной железы происходит после трансплантации почки [ 25 ][ 43 ]. Так, исследование Kumar R. и соавт.…”

Section: тиреотропный гормонunclassified

“…Так, исследование Kumar R. и соавт. (2014) продемонстрировало, что снижение концентрации ТТГ и свободного Т3 развивается к концу первого месяца после трансплантации почки [ 25 ].…”

Section: тиреотропный гормонunclassified

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Pituitary disorders in patients with end-stage chronic renal failure

Markova,

Kosova,

Mishchenko

2024

Probl Endokrinol (Mosk)

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Disorders in the kidneys lead to disturbance of homeostasis. As the glomerular filtration rate decreases, the metabolism of numerous biologically active substances, including pituitary hormones, decreases. The article presents an overview of pituitary dysfunction in patients with chronic kidney disease (CKD) and discusses the possible reasons of the pathogenetic mechanisms. Particular focus is being given to the assessment of changes in the concentration of pituitary hormones in patients with end-stage chronic kidney disease (CKD) and discusses the pathogenetic mechanisms of their formation. Particular attention is paid to the assessment of changes in the concentration of pituitary hormones in patients receiving renal replacement therapy (RRT). CKD leads to an increase in the level of prolactin, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Concentrations of growth hormone (GH), isulin-like growth factor-1 (IGF-1), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH) and vasopressin may remain within normal values or increase in this group of patients. RRT does not reduce the levels of prolactin, LH, FSH, while the concentration of growth hormone, IGF-1, TSH tends to normalize. The content of ACTH and vasopressin may remain unchanged or decrease. Kidney transplantation in most cases corrects hormonal disorders. Correction of hormonal changes can improve the clinical outcome and quality of life of patients with end stage CKD.

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Section: пролактинunclassified

Section: гонадотропиныunclassified

Section: тиреотропный гормонunclassified

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Pituitary disorders in patients with end-stage chronic renal failure

Markova,

Kosova,

Mishchenko

2024

Probl Endokrinol (Mosk)

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Editorial

Sharma

2014

Indian Journal of Transplantation

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Stress Analysis of Endodontically Treated Tooth–Implant Different Connectors Designs in Maxillary Posterior Region: A Finite Element Analysis

Hashemi,

Baghaei,

Fathi

et al. 2023

Eur J Dent

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Objectives Using finite element analysis (FEA), this study aimed to determine the effect of nonrigid connectors (NRCs) and their position on the success of tooth and implant-supported fixed prostheses in the maxillary posterior region. Materials and Methods Three three-dimensional FEA models were designed, presuming maxillary second premolar and first molar to be extracted. Implant (replacing first molar), abutment, bone (spongious and cortical), first premolar (containing dentin, root cement, gutta-percha, and casting post and core), periodontal ligament, and three three-unit cemented porcelain-fused-to-metal prostheses (a rigid one and two nonrigid) were modeled. The NRC was once on the tooth side and once on the implant side. The prostheses were loaded twice. The first molar (180 N) and premolars (120 N) teeth were subjected to progressive vertical and oblique (12-degree) loads, and maximum von Mises stress and strain in teeth and connectors were calculated for each model. Results The findings of the current study showed evidence that tooth-implant design with an NRC has significantly increased the average stress in the tooth. The average stress in dentin was 769.02 for the mesial connector and 766.95 for the distal connector, and this was only 731.59 for rigid connector. Furthermore, it was observed that rigid connector has considerably minimized the stress within the tooth–implant-supported fixed partial denture. The average stress for the crown and metal frame is 346.22 and 526.41 in rigid connector, while it is 1,172.9 and 2,050.9 for the nonrigid mesial connector. Conclusion Although distal NRC was more efficient than mesial NRC, using NRC will only reduce the stress applied to cortical bone and is not recommended in the posterior region of the maxilla.

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Effect of renal transplantation on multiple hormone levels in patients of chronic kidney disease: A single center study

Cited by 3 publications

References 16 publications

Pituitary disorders in patients with end-stage chronic renal failure

Pituitary disorders in patients with end-stage chronic renal failure

Editorial

Stress Analysis of Endodontically Treated Tooth–Implant Different Connectors Designs in Maxillary Posterior Region: A Finite Element Analysis

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