Effect of Recombinant Human Parathyroid Hormone (1-84) on Resolution of Active Charcot Neuro-osteoarthropathy in Diabetes: A Randomized, Double-Blind, Placebo-Controlled Study
Abstract:<b>Objectives</b>:
Fractures in Charcot neuro-osteoarthropathy (CN) often fail to heal despite
prolonged immobilization with below-knee casting. The aim of the study was to
assess the efficacy of recombinant human parathyroid hormone (PTH) in reducing
time to resolution of CN and healing of fractures.
<p><b>Research Design and
Methods</b>: People with diabetes and acute (active) Charcot foot were
randomized (double-blind) to either full length PTH (1-84) or placebo therapy -
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