Effect of Recombinant HCG Pretreatment on Surgical Sperm Retrieval Rates in Patients With Non-Obstructive Azoospermia – An Audit of Our Practice

Abstract

significantly associated with older maternal age (R¼-0.27, p<0.01), fewer 2PNs, higher aneuploidy rate, and fewer usable embryos for transfer. (Table 1)However, when controlling for maternal age using multivariate regression analysis, AMH was not an independent predictor of the rate of aneuploid embryos (p¼0.11) CONCLUSIONS: AMH is an established marker of ovarian reserve and is predictive of the number of embryos available for biopsy, however our results suggest that it is not an independent predictor of blastocyst euploidy rates. This is important information for both obstetrician/gynecologists and reproductive endocrinologists when counseling patients with diminished ovarian reserve prior to undergoing IVF.

Does hormonal therapy improve sperm retrieval rates in men with non-obstructive azoospermia: a systematic review and meta-analysis

“…Finally, when the only study not published as a full text ( Sen et al , 2020 ) was excluded, there was a non-statistically significant trend towards a higher SSR in the normogonadotropic group compared to the hypergonadotropic cohort (OR 1.9, 95% CI: 0.95–3.78, P = 0.07).…”

“…Of the retrieved texts, we analysed 10 studies ( Tables I and II ). Among them, five studies ( Reifsnyder et al , 2012 ; Shiraishi et al , 2012 ; Majzoub et al , 2016 ; Hu et al , 2018 ; Amer et al , 2020 ) included hypergonadotropic subjects whereas five ( Aydos et al , 2003 ; Hussein et al , 2013 ; Gul, 2016 ; Cocci et al , 2018 ; Sen et al , 2020 ) included normogonadotropic men. The characteristics of the retrieved studies are reported in Tables I and II .…”