Effect of Radish Leaves Powder on the Gastrointestinal Function and Fecal Triglyceride, and Sterol Excretion in Rats Fed a Hypercholesterolemic Diet

Abstract

The current study examined the effects of radish leaves powder on the excretion of fecal triglyceride, and sterol and hepatic UDP-glucuronyl transferase (UDPGT) activity in rats fed hypercholesterolemic diet. Male Sprague-Dawley rats weighing 100±10 g were randomly assigned to normal control group (N group), normal diet with 5% radish leaves powder supplemented group (NR) and hypercholesterolemic groups, which were subdivided into radish leaves powder free diet group (HC) and 2.5% (HRL), 5% (HRM), and 10% (HRH) radish leaves powder supplemented groups. The experimental diets were fed ad libitum for 4 weeks. Fecal weights and water contents were significantly increased in all radish leaves powder supplemented groups (NR, HRL, HRM, and HRH) than that of N and HC groups. Fecal total lipid contents including fecal neutral and acidic sterols in radish leaves powder supplemented groups were higher than those of the HC group, and especially that of HRH group was the highest among all experimental groups. Hepatic UDPGT activity of HRH group was 38% higher than that of HC group. Excretions of fecal bile acid were increased 2.3 and 2.7 folds in HRM and HRH groups compared with that of HC group. And neutral sterol, coprostanol, and coprostanone contents of them were higher in radish leaves supplemented groups than in HC group. These results suggest that radish leaves may act as potential substitute for a dietary fiber capable of improving a gastrointestinal function and lipid metabolism.

Effect of Enzyme-Treated Radish Leaves on Lipid Metabolism in Rats Fed a High-Fat Diet

“…The findings of the current study agree with the result of Jang et al (27) in which the feces, total lipid, total cholesterol, and TG contents were increased by feeding with untreated radish leaves, and the physiological effects of dietary fiber and flavonoids were reported by Kang et al (2) The enzymatic treatment of radish leaves increases the useful dietary fiber contents and the previous results can indicate that enzyme-treated radish leaves are more effective in increasing water-SDF levels than non enzyme-treated radish leaves. The findings of the current study also agree with the result of Yim et al (36) where glucomannan, an SDF, reduced weight while significantly decreasing dry weight water and fat contents, helping excretion with no side effects.…”

“…Thus, SDF content of enzyme-treated radish leaves is greater than untreated radish leaves. Jang et al (27) reported that ginger contained nearly 6.0% crude fiber, which increased to 15.7% after zymolysis. Radish leaves were also found to have higher levels of IDF and SDF through enzyme treatment, indicating that TDF content increased.…”

Effects of Portulaca oleracea Powder on the Lipid Levels of Rats Fed a Hypercholesterolemia Inducing Diet

“…Such increases were caused by dietary fiber and flavonoids in the plants (40). Notably, quercetin, which is a kind of flavonoid, decreases the serum cholesterol and LDL-C level by suppressing the activity of the HMG-Co A reductase within liver tissue and controlling the formation of cholesterol in body (41).…”

Редис (лат. radix)

“…Клетчатка устраняет запоры и прочищает ЖКТ, вбирая в себя токсичные элементы. Кстати, в одном из исследований на крысах корейские учёные заметили, что не только сам корнеплод, но и листья растения способствуют нормализации работы желудка и кишечника [9] . Помимо этого, редис стимулирует выработку желчи, которая также необходима для процесса пищеварения.…”