Effect of Quality of Life Impact and Clinical Severity on Adherence to Topical Acne Treatment

Tan, Jerry; Balagurusamy, Madhan K; Fung, Karen Y.; Gupta, Aditya K.; Thomas, David; Sapra, Sheetal; Lynde, Charles; Poulin, Yves; Gulliver, Wayne; Sebaldt, Rolf J.

doi:10.2310/7750.2009.08055

Cited by 21 publications

(36 citation statements)

References 19 publications

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“…In standard clinical practice, patients with greater acne severity have been shown to be less compliant to topical therapy. 17 In a clinical trial setting, these subjects may be more motivated to adhere to treatment, particularly if it is convenient, rapid in onset, and capable of maintaining ongoing improvement.…”

Section: Discussionmentioning

confidence: 99%

The efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesions

Feldman

Tan

Poulin

et al. 2011

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

The efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesions

Feldman

Tan

Poulin

et al. 2011

Journal of the American Academy of Dermatology

Self Cite

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“…Dreno et al [4] also found a risk of poor adherence of 60% among patients taking a combination of both systemic and topical therapy, and a higher likelihood of poor adherence to the systemic arm of treatment compared to the topical arm (54 vs. 44%, respectively). Other studies utilizing questionnaires and/or single questions to assess adherence have found rates of poor adherence ranging from 76 to 0% [2,3,5,15,16,17]. Studies using objective measures such as not keeping appointments, pill counts, weighing medication, number of medication refills, and electronic caps have reported adherence rates ranging from 28 to 88.3% [6,7,8,18].…”

Section: Discussionmentioning

confidence: 99%

“…Some studies have evaluated adherence to acne medications in various parts of the world [2,3,4,5,6,7,8]; however, there are few data specific to Japan. This study was designed to assess adherence among acne patients in Japan, to determine if there are differences in adherence based on type of treatment (topical or oral), and to evaluate the factors that can affect adherence to acne treatment.…”

Section: Introductionmentioning

confidence: 99%

Acne Management in Japan: Study of Patient Adherence

et al. 2011

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Obtaining good adherence to acne therapy is a challenge for all dermatologists. We studied 428 acne patients in Japan to determine the likelihood of good adherence and factors associated with medication-taking. This study utilized a simple validated questionnaire to assess risk of poor adherence; information about patient and treatment characteristics was also collected. There was an overall rate of poor adherence in 76% of subjects. Adherence to topical medication was poor in 52% of those treated with a topical agent only (n = 123). Among those taking combination therapies (n = 275), adherence to the topical portion of therapy was poor in 49% of subjects. The likelihood of poor adherence to oral medication was higher, both when administered alone (n = 30, 93% poor adherence) and when given as part of a combination regimen (n = 275, 86%). Factors with an impact on adherence included satisfaction with treatment (p = 0.023) and the experience of side effects (p = 0.027). Patients who felt they had a good understanding of acne and its treatment were more likely to have good adherence. These data suggest that there is significant room for improvement in acne adherence in Japan, as in other areas of the world, and that improved education may enhance adherence.

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“…In dermatology, it can be assessed on generic scales, generic dermatological scales and disease-specific scales [5,6]. It is important to consider this QoL as part of an overall patient management as it has a positive impact on satisfaction regarding care, compliance and therapeutic outcome [3,7,8,9]. The presence of apparent lesions is associated with reduced QoL, especially in patients <40 years old [10,11] and in patients suffering from acne [12,13,14,15,16].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Quality of Life after a Medical Corrective Make-Up Lesson in Patients with Various Dermatoses

et al. 2012

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Background: Apparent skin lesions can impair quality of life (QoL). Objective: To assess QoL improvement brought by a medical corrective make-up lesson and its daily use in practice using the Dermatology Life Quality Index (DLQI). Methods: Patients with facial disorders participating during 2 years in our lessons conducted by a trained nurse were included in an open prospective study. Results: 86 patients aged 4–79 years were included. They suffered from acne (25), rosacea (10), scars (14) and various dermatoses (19). 63 patients (73%) sent back the questionnaire. One-month DLQI improvement was significant (p < 0.001) in acne (p = 0.006) as well as rosacea (p = 0.036), with a trend for scars (p = 0.057). QoL significantly improved, independently of a low (p < 0.001) or high (p = 0.006) initial DLQI. Since the lesson, 95% of patients re-made up with 97% of good tolerance. Conclusion: This is the first study examining at-home make-up completion and showing the beneficial effect of a medical corrective make-up lesson on the QoL of patients with various facial dermatoses in France.

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Effect of Quality of Life Impact and Clinical Severity on Adherence to Topical Acne Treatment

Abstract: Adherence to topical acne therapy increases with impact on QoL but decreases with increasing acne severity.

Cited by 21 publications

References 19 publications

The efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesions

The efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesions

Acne Management in Japan: Study of Patient Adherence

Evaluation of Quality of Life after a Medical Corrective Make-Up Lesson in Patients with Various Dermatoses

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