Effect of psychopharmacotherapy on suicide risk in discharged psychiatric inpatients

Modestin, Jiří; Schwarzenbach, F.

doi:10.1111/j.1600-0447.1992.tb01464.x

Cited by 54 publications

(21 citation statements)

References 16 publications

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“…Significantly higher proportion of controls than suicide completers across studies was on lithium. [192342] However, we did not find such difference on lithium use between groups. Among antidepressants norepinephrine and specific serotonergic antidepressants (noradrenergic and specific serotonergic antidepressants) and serotonin and norepinephrine reuptake inhibitor predicted suicide risk among inpatients with affective disorder.…”

Section: Discussioncontrasting

confidence: 74%

Inpatient Suicide in a Psychiatric Hospital: A Nested Case-control Study

Khanra

Mahintamani

Bose

et al. 2016

Indian Journal of Psychological Medicine

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Objective:Risk factors for inpatient suicide are different from those in the general population. We examined sociodemographic and clinical variables of patients who committed suicide as an inpatient in a psychiatric hospital in India.Methods:Matched retrospective nested case–control design was adopted. Ten patients who died by suicide as inpatients between 2000 and 2013 were included, along with fifty controls, matched with respect to age, sex, diagnosis, and period of admission.Results:Suicide completers were mostly unskilled in occupation (P = 0.03), had a history of past suicide attempts (P < 0.001), shorter duration of hospital stay (P = 0.001), poorer improvement on psychopathology (P = 0.02), and were having more suicidal ideation (P = 0.02). Significantly more completers were receiving antidepressants (P = 0.04).Conclusion:This study adds to the existing sparse literature on inpatient suicides from Asia. Strength of the study was close matching between case and controls and blindedness. Limitations were retrospective design, and variations in prescription behavior and treatment decisions.

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Section: Discussioncontrasting

confidence: 74%

Inpatient Suicide in a Psychiatric Hospital: A Nested Case-control Study

Khanra

Mahintamani

Bose

et al. 2016

Indian Journal of Psychological Medicine

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“…The role of lithium in suicide prevention in affective disorders has also received some attention. Modestin and Schwarzenbach (1992) matched 64 inpatients who later committed suicide with 64 inpatients who did not. In their sample, 45% had mood disorders.…”

Section: Somatic Treatment Strategiesmentioning

confidence: 99%

Suicide: Risk factors and prevention in refractory major depression

1997

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The literature regarding risk factors for suicidal behavior in the context of major depressive episode is reviewed. An organized framework for prevention strategies is provided. Risk factors for suicide in major depression can be organized according to whether their effect is on the threshold for suicidal acts or whether they serve mainly as triggers or precipitants of suicidal acts. For patients sufficiently depressed to present for evaluation and treatment, severity of depression is a poor guide to risk for suicidal acts. The best predictors relate to the threshold or predisposition to suicidal acts in response to major depression. Although available literature on suicidal behavior focuses on major depression in general, the findings may be usefully applied in refractory depression. Guidelines for assessment and management of suicidal behavior in major depression are offered. Depression and Anxiety 5:202–211, 1997. © 1997 Wiley‐Liss, Inc.

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“…Several studies have reported a correlation between shorter lengths of stay and higher suicide risk postdischarge (Desai, Dausey, & Rosenheck, 2005;Modestin & Schwartzenbach, 1992;Modestin, Schwarzenbach, & Wurmle, 1992;Qin & Nordentoft, 2005). On the other hand, Ho (2003) found a correlation between shorter lengths of stay and lower risk.…”

mentioning

confidence: 92%