Effect of psychological stress on airway impedance in individuals with asthma and panic disorder.

Abstract

The authors assessed airway impedance responses to psychological stressors among 113 individuals: 61 with asthma only (AS), 10 with asthma and panic disorder (ASPD), 24 with panic disorder only (PD), and 18 controls with neither condition (CON). Individuals with either AS or PD were affected by psychological stressors as measured by the forced oscillation technique. Individuals with PD (with or without AS) displayed lower airway impedance than those without PD. These data suggest that the airways of individuals with PD are in a chronic state of preparedness, which may promote hyperventilation.

Depression in Asthma: Prevalence and Clinical Implications

“…If confirmed, the increased mortality risk may be consistent with data suggesting increases in cholinergically mediated airway constriction associated with stress or negative mood states. [59][60][61] However, other data suggest that depressed patients subjectively perceive themselves as having more severe asthma symptoms than euthymic patents, but this perception is not supported by objective measures of disease severity. 43,45,47 In addition, preliminary data from our group suggest less severe airway obstruction, as measured with spirometry, in asthma patients with a history of a mood disorder than in those without a mood disorder.…”

Medicação antipânico e função pulmonar em pacientes com transtorno de pânico

“…Por outro lado, Carr et al 17 observaram que os pacientes com TP apresentaram vias aéreas mais dilatadas tanto em resposta a tarefas estressantes como não estressantes. Embora as manobras de capacidade vital forçada pudessem aumentar os níveis de ansiedade em pacientes com TP por causa da hiperventilação e das interpretações catastróficas dos sintomas respiratórios 32 , principalmente após a inalação do salbutamol, observou-se que a mediana do SUDS variou de 1 a 3 (Figura 1), sem uma diferença significativa.…”

“…Esses achados, contudo, não foram replicados 16 . Carr et al 17 avaliaram a impedância das vias aéreas em resposta a estressores psicológicos em 113 sujeitos alocados em 4 grupos: 61 asmáticos, 10 asmáticos com TP, 24 com TP e 18 controles saudáveis. Eles concluíram que pacientes com TP (com ou sem asma) apresentaram menor impedância de vias aéreas (vias aéreas mais dilatadas) do que aqueles sem TP, sugerindo um sistema respiratório mais preparado para reagir ao estresse.…”

Prevalence of hyperventilation syndrome in an allergy clinic, compared with a routine ENT clinic

“…1 -4 Hyperventilation may be a result of the increased anxiety found in some asthmatic patients, 2 suggesting that there may be a high prevalence of hyperventilation in patients with other allergic diseases as well. Furthermore, understanding the existence of this condition in allergic patients might be beneficial when treating these patients.…”