Effect of propranolol versus no antiarrhythmic drug on sudden cardiac death, total cardiac death, and total death in patients ≥62 years of age with heart disease, complex ventricular arrhythmias, and left ventricular ejection fraction ≥40%

Aronow, Wilbert S.; Ahn, Chul; Mercando, Anthony D.; Epstein, Stanley; Kronzon, Itzhak

doi:10.1016/0002-9149(94)90369-7

Cited by 88 publications

(42 citation statements)

References 12 publications

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“…22,286 Beta blockers should also be considered in treatment of elderly persons with complex ventricular arrhythmias with abnormal 684 or normal 685 ejection fraction. Beta blockers are also useful to treat elderly persons with hypertension who have hyperthyroidism, preoperative hypertension, migraine, or essential tremor.…”

Section: Percutaneous Renal Artery Stentingmentioning

confidence: 99%

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

et al. 2011

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Section: Percutaneous Renal Artery Stentingmentioning

confidence: 99%

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

et al. 2011

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“…Aronow and colleagues [28] found that silent ischemia was present in 27% and CVA in 69% of uremic patients older than 65 years. In another trial, silent ischemia was noted in 15.5% of patients undergoing 48-hour Holter monitorization.…”

Section: Factors Causing Arrhythmia In Esrdmentioning

confidence: 98%

Prevalence and Predictors of Arrhythmia in End Stage Renal Disease Patients on Hemodialysis

et al. 2007

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“…Beta blockers such as propranolol 10 mg to 30 mg given 3 to 4 times daily can be administered to control ventricular arrhythmias 144 and after conversion of AF to sinus rhythm. Should AF recur, beta blockers have the added advantage of slowing the ventricular rate.…”

Section: Ventricular Rate Controlmentioning

confidence: 99%

Atrial Fibrillation: The New Epidemic of the Ageing World

Aronow¹,

Banach²

2009

J.A.F.I.B

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The prevalence of atrial fibrillation (AF) increases with age. As the population ages, the burden of AF increases.AF is associated with an increased incidence of mortality, stroke, and coronary events compared to sinus rhythm. AF with a rapid ventricular rate may cause a tachycardia-related cardiomyopathy. Immediate direct-current (DC) cardioversion should be performed in patients with AF and acute myocardial infarction, chest pain due to myocardial ischemia, hypotension, severe heart failure, or syncope. Intravenous beta blockers, diltiazem, or verapamil may be administered to reduce immediately a very rapid ventricular rate in AF. An oral beta blocker, verapamil, or diltiazem should be used in persons with AF if a fast ventricular rate occurs at rest or during exercise despite digoxin. Amiodarone may be used in selected patients with symptomatic life-threatening AF refractory to other drugs. Digoxin should not be used to treat patients with paroxysmal AF. Nondrug therapies should be performed in patients with symptomatic AF in whom a rapid ventricular rate cannot be slowed by drugs. Paroxysmal AF associated with the tachycardia-bradycardia syndrome should be treated with a permanent pacemaker in combination with drugs. A permanent pacemaker should be implanted in patients with AF and symptoms such as dizziness or syncope associated with ventricular pauses greater than 3 seconds which are not drug-induced. Elective DC cardioversion has a higher success rate and a lower incidence of cardiac adverse effects than does medical cardioversion in converting AF to sinus rhythm. Unless transesophageal echocardiography has shown no thrombus in the left atrial appendage before cardioversion, oral warfarin should be given for 3 weeks before elective DC or drug cardioversion of AF and continued for at least 4 weeks after maintenance of sinus rhythm. Many cardiologists prefer, especially in elderly patients , ventricular rate control plus warfarin rather than maintaining sinus rhythm with antiarrhythmic drugs. Patients with chronic or paroxysmal AF at high risk for stroke should be treated with long-term warfarin to achieve an International Normalized Ratio of 2.0 to 3.0. Patients with AF at low risk for stroke or with contraindications to warfarin should be treated with aspirin 325 mg daily

show abstract

Effect of propranolol versus no antiarrhythmic drug on sudden cardiac death, total cardiac death, and total death in patients ≥62 years of age with heart disease, complex ventricular arrhythmias, and left ventricular ejection fraction ≥40%

Cited by 88 publications

References 12 publications

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

Prevalence and Predictors of Arrhythmia in End Stage Renal Disease Patients on Hemodialysis

Atrial Fibrillation: The New Epidemic of the Ageing World

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