Approved
REPOT DCUMETATON PGE
0MB No. 0704-0 188Pulc mpoillng r this coZetinof infrmnation is estimnated to average 1 hoa, per response, indtwng the firm for revewing instructions. sean:-rhg adeltg dtal swum,. gathering and rnsinrWt tMe daeta needed. and compleVn and re'Aww4ng thi collection of infornmtton-Send cownmits regaintog ths brden aistmate or any other aspect of tlift cottedl ofn cE rrifot, ýnLtdtucng suggestorm for nicking 14. ABSTRACT Background. NASA has need of a rapid, reliable and non-invasive means to objectively evaluate the cognitive ability of astronauts to perform ruission critical tasks, particularly during extended duration space flight. One such means under consideration is the Space flight-Cogniitive Assessment Tool (S-CAT), a tool designed to assesis cognitive performsance using a set of five cogntive performancetesut. The current study had multiple goals, one of whic~h was to evaluate the sensitivity of S-CAT to fatigue induced by sleep deprivailon and circadian disruption. Research Hypothesis. Since S-CAT has demonstrated sensitivity to organic neural dysfunction, it was expected to show fatigue sensitivity. Methods. Two groups of eight US mtifitary pilots (ages 30-40) were deprived of sleep for 40Inhs, over two circadian performance nadirs. In addition to S-CAT, four other cognitive performance tests were performed reputedly during the sleep deprivation period. The S-CAT bauery of tasks was performied once evety six hours up to the 33rd hour whiu lthe participants were in the experimental situation. Results. For all tests, the response time measures showed the greatest effcclN fromn fatigue. Two of the five S-CAT tests, the Matching to Sample and the Math tests, exhibited significant fatiguerelated de-cremLTita on response time. The M~atching to Sample test and the Continuous Processing test showed effec-ts on accuray and percent corrcct. F~or Continuous Processing, 4 of 6 trials were affected, beginning after 23 hrs of wakefulness and lasting until 35 hours awake-Pilovism-a to be somewhat less Xuhnerable