Effect of process variables on the preparation of artificial bone cements

Santos, Jorge Gomes; Pita, Victor Jayme Roget Rodriguez; Melo, Prı́amo A.; Nele, Márcio; Pinto, José Carlos

doi:10.1590/s0104-66322013000400018

Cited by 6 publications

(2 citation statements)

References 27 publications

(27 reference statements)

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“…The term “bone cement” refers to artificial bone materials based on polymethyl methacrylate (PMMA) or other acrylate-based polymers [1,2,3]. The scope of medical applications of cement materials primarily involves fixing endoprostheses in total knee arthroplasty (TKA) and total hip arthroplasty (THA).…”

Section: Introductionmentioning

confidence: 99%

Effect of Physiological Fluids Contamination on Selected Mechanical Properties of Acrylate Bone Cement

2019

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This study analyses the degradation rate of selected mechanical properties of bone cement contaminated with human blood and saline solution. During the polymerisation stage, the PMMA cement specimens were supplemented with the selected physiological fluids in a range of concentrations from 0% to 10%. The samples were then subjected to the standardised compression tests, as per ISO 5833: 2002, and hardness tests. The obtained results were analysed statistically to display the difference in the degradation of the material relative to the degree of contamination. Subsequently, numerical modelling was employed to determine the mathematical relationship between the degree of contamination and the material strength degradation rate. The introduction of various concentrations of contaminants into the cement mass resulted in a statistically significant change in their compressive strength. It was shown that the addition of more than 4% of saline and more than 6% of blood (by weight) causes that the specimens exhibit lower strength than the minimum critical value of 70 MPa, specified in the abovementioned International Standard. It was further revealed that the cement hardness characteristics degraded accordingly. The mathematical models showed a very good fit with the results from the experiments: The coefficient of determination R2 was 0.987 in the case of the linear hardness model for blood and 0.983 for salt solution; secondly, the values of R2 for the third-degree polynomial model of compressive strength were 0.88 for blood and 0.92 for salt. From the results, it can be seen that there is a quantitative/qualitative relationship between the contamination rate and the drop in the tested mechanical characteristics. Therefore, great effort must be taken to minimise the contact of the bone cement with physiological fluids, which naturally occur in the operative field, particularly when the material cures, in order to prevent the cement material strength declining below the minimum threshold specified in the ISO standard.

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Section: Introductionmentioning

confidence: 99%

Effect of Physiological Fluids Contamination on Selected Mechanical Properties of Acrylate Bone Cement

2019

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“…Specific procedures are described by PMMA bone cement manufacturers, but sometimes, in practice, given uncontrollable factors as operating room and patient temperature or even the cement thickness, the prescribed times might be altered: either delayed or sped up, depending on the situation [26].…”

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Influence of the Bone Cements Processing on the Mechanical Properties in Cranioplasty

Riviș¹,

Pricop²,

Talpoș³

et al. 2018

Rev. Chim.

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The aim of this study is to observe the time of mixing influence on the properties of commercially available PMMA bone cement, widely used in cranioplasty. The studied bone cement is provided in the form of a solid powder (the copolymer) and a liquid monomer. The increase of the mixing phase duration and the use of two mixing methods (manual and mechanical) effect on surface and mechanical characteristics were studied. The samples were prepared as if in the operation room. Surface characteristics were studied by means of contact angle measurements, morphology by scanning electron microscopy (SEM) and mechanical characteristics determined by flexural tests in a three point bending configuration. The conclusion of this study is that by using a mechanical mixing method and increasing mixing time higher flexural strength can be achieved by reducing pore content within bone cement.

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Synthesis, characterization and thermal properties of PMMA/CuO polymeric nanocomposites

Soleimani

Moghaddami

2017

J Mater Sci: Mater Electron

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Effect of process variables on the preparation of artificial bone cements

Cited by 6 publications

References 27 publications

Effect of Physiological Fluids Contamination on Selected Mechanical Properties of Acrylate Bone Cement

Effect of Physiological Fluids Contamination on Selected Mechanical Properties of Acrylate Bone Cement

Influence of the Bone Cements Processing on the Mechanical Properties in Cranioplasty

Synthesis, characterization and thermal properties of PMMA/CuO polymeric nanocomposites

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