Effect of preventive (  blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial

Holroyd, Kenneth A.; Cottrell, Constance; O’Donnell, Francis; Cordingley, Gary E.; Drew, Jana Brittain; Carlson, Bruce W.; Himawan, Lina K.

doi:10.1136/bmj.c4871

Cited by 180 publications

(186 citation statements)

References 84 publications

(86 reference statements)

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“…Two studies presented results of non-pharmacological treatments, the first was based on a patient education programme [15] and the second on osteopathic manipulative treatment [16]. Finally, the two trials on b-blockers also included a behavioural management approach in migraine treatment [7,8].…”

Section: Resultsmentioning

confidence: 99%

“…There were one trial on onabotulium toxin A [5], three trials on prophylactic medications, one on levetiracetam [6] and two on b-blockers [7,8]. Four studies described a surgical approach: two were procedures for deactivation of trigger sites [9,10], one approach was the occipital nerve stimulation [11], and one approach was bariatric surgery for obese patients patients comorbid migraine [12].…”

Section: Resultsmentioning

confidence: 99%

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Disability and quality of life in headache: where we are now and where we are heading

D’Amico¹,

Grazzi²,

Usai³

et al. 2013

Neurol Sci

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Headache disorders determine relevant personal and societal burden, and thus the use of patient-reported outcome measures (PROMs) investigating the level of disability and health-related quality of life (HRQoL) have been increasingly used in headache research. The aim of this review was to address the status of research on disability and HRQoL, by addressing results from recently published clinical trials as well as in longitudinal observational studies on headache patients. PubMed has been searched for papers in which measures of HRQoL and/or disability were used as primary or secondary outcome on adult subjects with primary headache, and published in 2010-2012. Among the 70 records retrieved, 12 papers were selected for narrative synthesis. They included data on 2,621 patients with episodic migraine with and without aura, chronic daily headache, and/or chronic migraine with and without medication overuse. The selected trials investigated the efficacy of different pharmacological prophylaxis, of some surgical approaches, of education programmes and osteopathic manipulative treatment; two studies reported longitudinal observations of patients currently under treatment. Overall, the results of our review showed that headache frequency as well as HRQoL and disability were positively impacted by treatment interventions; positive outcomes were less evident in two studies, and similar results were found in the two observational studies. Our findings confirmed that the most commonly used PROMs, including disease-specific tools to assess disability and HRQoL and SF-36, are sensitive to the beneficial effects occurring over time in functioning and quality of life domains in headache patients. They also suggest that the personal and societal costs of headache disorders are likely to be reduced when headache patients receive appropriate treatments and when continuity of care is offered. In terms of future directions, we note that the systematic use of appropriate PROMs should be encouraged both in the clinical practice and in the research field, as they offer a valid option to assess the global effect of treatments on patient-perceived sense of well-being and quality of performance.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Disability and quality of life in headache: where we are now and where we are heading

D’Amico¹,

Grazzi²,

Usai³

et al. 2013

Neurol Sci

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“…In high-frequency migraine (mean 5.5 migraine days/month), addition of behavioural management alone to optimized acute treatment had no significant effect, whereas the combination of behavioural therapy with a beta blocker significantly improved outcome at 16 months [113].…”

Section: Cognitive-behavioural Therapymentioning

confidence: 94%

Diagnosis, pathophysiology and management of chronic migraine: a proposal of the Belgian Headache Society

Paemeleire

Louis²,

Magis

et al. 2014

Acta Neurol Belg

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Chronic migraine (CM) is a disabling neurological condition affecting 0.5-2 % of the population. In the current third edition of the International Classification of Headache Disorders, medication overuse is no longer an exclusion criterion and CM is diagnosed in patients suffering from at least 15 headache days per month of which at least eight are related to migraine. CM is difficult to treat, and preventive treatment options are limited. We provide a pathogenetic model for CM, integrating the latest findings from neurophysiological and neuroimaging studies. On behalf of the Belgian Headache Society, we present a management algorithm for CM based on the international literature and adapted to the Belgian situation. Pharmacological treatment options are discussed, and recent data on transcranial and invasive neuromodulation studies in CM are reviewed. An integrated multimodal treatment programme may be beneficial to refractory patients, but at present, this approach is only supported by a limited number of observational studies and quite variable between centres

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“…Another important component of our variable includes mental health counseling and stress management therapy, which as Dr. Solomon notes has been shown in various forms to improve headache symptoms in systematic reviews and randomized controlled trials. 4,5 …”

mentioning

confidence: 99%

Trends in the Management of Headache

et al. 2015

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Effect of preventive ( blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial

Abstract: Objective To determine if the addition of preventive drug treatment (β blocker), brief behavioural migraine management, or their combination improves the outcome of optimised acute treatment in the management of frequent migraine.

Cited by 180 publications

References 84 publications

Disability and quality of life in headache: where we are now and where we are heading

Disability and quality of life in headache: where we are now and where we are heading

Diagnosis, pathophysiology and management of chronic migraine: a proposal of the Belgian Headache Society

Trends in the Management of Headache

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